ID   AKTIP_CULQU             Reviewed;         231 AA.
AC   B0X6E8;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Protein crossbronx homolog;
GN   ORFNames=CPIJ015056;
OS   Culex quinquefasciatus (Southern house mosquito) (Culex pungens).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Culicini; Culex; Culex.
OX   NCBI_TaxID=7176;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JHB;
RG   The Broad Institute Genome Sequencing Platform;
RA   Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D.,
RA   Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., Mauceli E.,
RA   Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., Amedeo P.,
RA   Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., Camaro F.,
RA   Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., Lawson D.,
RA   Montgomery P., Nene V., Nusbaum C., Puiu D., Romero-Severson J.,
RA   Severson D.W., Shumway M., Sisk P., Stolte C., Zeng Q., Eisenstadt E.,
RA   Fraser-Liggett C.M., Strausberg R., Galagan J., Birren B., Collins F.H.;
RT   "Annotation of Culex pipiens quinquefasciatus.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. FTS
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU00388}.
CC   -!- CAUTION: Lacks the conserved Cys residue necessary for ubiquitin-
CC       conjugating enzyme E2 activity. {ECO:0000305}.
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DR   EMBL; DS232412; EDS41431.1; -; Genomic_DNA.
DR   RefSeq; XP_001865220.1; XM_001865185.1.
DR   AlphaFoldDB; B0X6E8; -.
DR   SMR; B0X6E8; -.
DR   STRING; 7176.CPIJ015056-PA; -.
DR   GeneID; 6048278; -.
DR   KEGG; cqu:CpipJ_CPIJ015056; -.
DR   VEuPathDB; VectorBase:CPIJ015056; -.
DR   VEuPathDB; VectorBase:CQUJHB010720; -.
DR   eggNOG; KOG0429; Eukaryota.
DR   HOGENOM; CLU_083049_1_0_1; -.
DR   InParanoid; B0X6E8; -.
DR   OMA; WGFPEWR; -.
DR   OrthoDB; 1226125at2759; -.
DR   PhylomeDB; B0X6E8; -.
DR   Proteomes; UP000002320; Partially assembled WGS sequence.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   Pfam; PF00179; UQ_con; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
DR   PROSITE; PS50127; UBC_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..231
FT                   /note="Protein crossbronx homolog"
FT                   /id="PRO_0000379028"
FT   DOMAIN          14..168
FT                   /note="UBC core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00388"
SQ   SEQUENCE   231 AA;  26270 MW;  427DC5C32E515C8B CRC64;
     MTLDSYDKLL GTVLQEYKIL TEYKRLQSED LGGIYVIPSH ENSFVWFGVL FVRSGPYKNG
     VFRFTLTLPD KFPNDSAVPT VVFQSETFHP LVCPYNGTLE LSEAFAKWKS GENHLWQVLK
     FIQYVFAHFE EYMAVAELTA NNVAHELFQQ SRADFLQRVE ECVRLSQAKV YDPAPVQDRN
     YIVFEQFDGA VHGPVLESMK QGRANEVGTT PPSSGLSWVK EGVFQPLSKQ G