FLGK_SALTY
ID FLGK_SALTY Reviewed; 553 AA.
AC P0A1J5; P15932;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Flagellar hook-associated protein 1;
DE Short=HAP1;
GN Name=flgK; Synonyms=flaS, flaW; OrderedLocusNames=STM1183;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2193164; DOI=10.1016/s0022-2836(05)80266-9;
RA Homma M., Derosier D.J., Macnab R.M.;
RT "Flagellar hook and hook-associated proteins of Salmonella typhimurium and
RT their relationship to other axial components of the flagellum.";
RL J. Mol. Biol. 213:819-832(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-21.
RX PubMed=2544561; DOI=10.1128/jb.171.7.3890-3900.1989;
RA Jones C.J., Homma M., Macnab R.M.;
RT "L-, P-, and M-ring proteins of the flagellar basal body of Salmonella
RT typhimurium: gene sequences and deduced protein sequences.";
RL J. Bacteriol. 171:3890-3900(1989).
RN [4]
RP PROTEIN SEQUENCE OF 2-6.
RX PubMed=2181149; DOI=10.1016/0022-2836(90)90132-6;
RA Jones C.J., Macnab R.M., Okino H., Aizawa S.;
RT "Stoichiometric analysis of the flagellar hook-(basal-body) complex of
RT Salmonella typhimurium.";
RL J. Mol. Biol. 212:377-387(1990).
CC -!- INTERACTION:
CC P0A1J5; P0A1J7: flgN; NbExp=3; IntAct=EBI-15610547, EBI-15610533;
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Bacterial flagellum
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the flagella basal body rod proteins family.
CC {ECO:0000305}.
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DR EMBL; X51738; CAA36025.1; -; Genomic_DNA.
DR EMBL; X51739; CAA36027.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20113.1; -; Genomic_DNA.
DR EMBL; M24466; AAA27071.1; -; Genomic_DNA.
DR PIR; S10366; SMEBH1.
DR RefSeq; NP_460154.1; NC_003197.2.
DR RefSeq; WP_000096425.1; NC_003197.2.
DR PDB; 2D4Y; X-ray; 2.10 A; A/B=66-527.
DR PDBsum; 2D4Y; -.
DR AlphaFoldDB; P0A1J5; -.
DR SMR; P0A1J5; -.
DR DIP; DIP-61313N; -.
DR IntAct; P0A1J5; 1.
DR STRING; 99287.STM1183; -.
DR PaxDb; P0A1J5; -.
DR EnsemblBacteria; AAL20113; AAL20113; STM1183.
DR GeneID; 1252701; -.
DR KEGG; stm:STM1183; -.
DR PATRIC; fig|99287.12.peg.1251; -.
DR HOGENOM; CLU_012762_0_1_6; -.
DR OMA; KPQAAYM; -.
DR PhylomeDB; P0A1J5; -.
DR BioCyc; SENT99287:STM1183-MON; -.
DR EvolutionaryTrace; P0A1J5; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:InterPro.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IBA:GO_Central.
DR InterPro; IPR001444; Flag_bb_rod_N.
DR InterPro; IPR019776; Flagellar_basal_body_rod_CS.
DR InterPro; IPR010930; Flg_bb/hook_C_dom.
DR InterPro; IPR002371; FlgK.
DR PANTHER; PTHR30033; PTHR30033; 1.
DR Pfam; PF00460; Flg_bb_rod; 1.
DR Pfam; PF06429; Flg_bbr_C; 1.
DR PRINTS; PR01005; FLGHOOKAP1.
DR TIGRFAMs; TIGR02492; flgK_ends; 1.
DR PROSITE; PS00588; FLAGELLA_BB_ROD; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Bacterial flagellum; Direct protein sequencing;
KW Reference proteome; Secreted.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:2181149"
FT CHAIN 2..553
FT /note="Flagellar hook-associated protein 1"
FT /id="PRO_0000180864"
FT HELIX 69..100
FT /evidence="ECO:0007829|PDB:2D4Y"
FT TURN 102..104
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 106..122
FT /evidence="ECO:0007829|PDB:2D4Y"
FT TURN 123..125
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 127..186
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 197..212
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 215..220
FT /evidence="ECO:0007829|PDB:2D4Y"
FT TURN 221..223
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 224..229
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 234..237
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 244..248
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 256..262
FT /evidence="ECO:0007829|PDB:2D4Y"
FT TURN 263..265
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 266..269
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 272..275
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 278..289
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 291..313
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 334..337
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 349..353
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 355..357
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 363..367
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 369..376
FT /evidence="ECO:0007829|PDB:2D4Y"
FT TURN 377..379
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 382..384
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 393..395
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 398..401
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 410..417
FT /evidence="ECO:0007829|PDB:2D4Y"
FT TURN 418..423
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 431..433
FT /evidence="ECO:0007829|PDB:2D4Y"
FT STRAND 437..439
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 454..460
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 461..464
FT /evidence="ECO:0007829|PDB:2D4Y"
FT TURN 469..471
FT /evidence="ECO:0007829|PDB:2D4Y"
FT HELIX 474..511
FT /evidence="ECO:0007829|PDB:2D4Y"
SQ SEQUENCE 553 AA; 59109 MW; 59C3EADF29C703AB CRC64;
MSSLINHAMS GLNAAQAALN TVSNNINNYN VAGYTRQTTI LAQANSTLGA GGWIGNGVYV
SGVQREYDAF ITNQLRGAQN QSSGLTTRYE QMSKIDNLLA DKSSSLSGSL QSFFTSLQTL
VSNAEDPAAR QALIGKAEGL VNQFKTTDQY LRDQDKQVNI AIGSSVAQIN NYAKQIANLN
DQISRMTGVG AGASPNDLLD QRDQLVSELN KIVGVEVSVQ DGGTYNLTMA NGYTLVQGST
ARQLAAVPSS ADPTRTTVAY VDEAAGNIEI PEKLLNTGSL GGLLTFRSQD LDQTRNTLGQ
LALAFADAFN AQHTKGYDAD GNKGKDFFSI GSPVVYSNSN NADKTVSLTA KVVDSTKVQA
TDYKIVFDGT DWQVTRTADN TTFTATKDAD GKLEIDGLKV TVGTGAQKND SFLLKPVSNA
IVDMNVKVTN EAEIAMASES KLDPDVDTGD SDNRNGQALL DLQNSNVVGG NKTFNDAYAT
LVSDVGNKTS TLKTSSTTQA NVVKQLYKQQ QSVSGVNLDE EYGNLQRYQQ YYLANAQVLQ
TANALFDALL NIR
