ID   FLGM_PROMI              Reviewed;          99 AA.
AC   P96974;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Negative regulator of flagellin synthesis;
DE   AltName: Full=Anti-sigma-28 factor;
GN   Name=flgM;
OS   Proteus mirabilis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Proteus.
OX   NCBI_TaxID=584;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=U6540;
RX   PubMed=9302021; DOI=10.1046/j.1365-2958.1997.5021862.x;
RA   Gygi D., Fraser G., Dufour A., Hughes C.;
RT   "A motile but non-swarming mutant of Proteus mirabilis lacks FlgN, a
RT   facilitator of flagella filament assembly.";
RL   Mol. Microbiol. 25:597-604(1997).
CC   -!- FUNCTION: Responsible for the coupling of flagellin expression to
CC       flagellar assembly by preventing expression of the flagellin genes when
CC       a component of the middle class of proteins is defective. It negatively
CC       regulates flagellar genes by inhibiting the activity of FliA by
CC       directly binding to FliA (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FlgM family. {ECO:0000305}.
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DR   EMBL; U82214; AAC45659.1; -; Genomic_DNA.
DR   RefSeq; WP_004243540.1; NZ_VKXK01000019.1.
DR   AlphaFoldDB; P96974; -.
DR   STRING; 584.AOUC001_07290; -.
DR   PATRIC; fig|584.131.peg.1973; -.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR035890; Anti-sigma-28_factor_FlgM_sf.
DR   InterPro; IPR007412; FlgM.
DR   InterPro; IPR031316; FlgM_C.
DR   Pfam; PF04316; FlgM; 1.
DR   SUPFAM; SSF101498; SSF101498; 1.
DR   TIGRFAMs; TIGR03824; FlgM_jcvi; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..99
FT                   /note="Negative regulator of flagellin synthesis"
FT                   /id="PRO_0000087285"
SQ   SEQUENCE   99 AA;  10625 MW;  78A466535D90A068 CRC64;
     MSIERTNPLI PITAISQRNL NEGAQEARKT GNAQTKAMAG DTSVKLSEAQ KKLVQPSNQD
     INVEKVARLK AAIADGTLTM DSSKIAEALF REAAESITK