ID   FLGM_YERE8              Reviewed;          99 AA.
AC   A1JT31; Q56891; Q57401;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 2.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Negative regulator of flagellin synthesis;
DE   AltName: Full=Anti-sigma-28 factor;
GN   Name=flgM; OrderedLocusNames=YE2562;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8830263; DOI=10.1046/j.1365-2958.1996.452978.x;
RA   Kapatral V., Olson J.W., Pepe J.C., Miller V.L., Minnich S.A.;
RT   "Temperature-dependent regulation of Yersinia enterocolitica class III
RT   flagellar genes.";
RL   Mol. Microbiol. 19:1061-1071(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081;
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the high
RT   pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- FUNCTION: Responsible for the coupling of flagellin expression to
CC       flagellar assembly by preventing expression of the flagellin genes when
CC       a component of the middle class of proteins is defective. It negatively
CC       regulates flagellar genes by inhibiting the activity of FliA by
CC       directly binding to FliA (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FlgM family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAL12603.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U16136; AAC43968.1; -; Genomic_DNA.
DR   EMBL; U37141; AAB52955.1; -; Genomic_DNA.
DR   EMBL; AM286415; CAL12603.1; ALT_INIT; Genomic_DNA.
DR   PIR; S71021; S71021.
DR   RefSeq; WP_005168786.1; NC_008800.1.
DR   RefSeq; YP_001006766.1; NC_008800.1.
DR   AlphaFoldDB; A1JT31; -.
DR   SMR; A1JT31; -.
DR   STRING; 393305.YE2562; -.
DR   EnsemblBacteria; CAL12603; CAL12603; YE2562.
DR   KEGG; yen:YE2562; -.
DR   PATRIC; fig|393305.7.peg.2720; -.
DR   eggNOG; COG2747; Bacteria.
DR   HOGENOM; CLU_149304_2_2_6; -.
DR   Proteomes; UP000000642; Chromosome.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR035890; Anti-sigma-28_factor_FlgM_sf.
DR   InterPro; IPR007412; FlgM.
DR   InterPro; IPR031316; FlgM_C.
DR   Pfam; PF04316; FlgM; 1.
DR   SUPFAM; SSF101498; SSF101498; 1.
DR   TIGRFAMs; TIGR03824; FlgM_jcvi; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..99
FT                   /note="Negative regulator of flagellin synthesis"
FT                   /id="PRO_0000285830"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..42
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   99 AA;  10727 MW;  024F21BBFD359776 CRC64;
     MSIDRTQPLL PVTPVQPRET SDIAQQTRKP SAQSKTPVSG TEVKLSDAQA KLMQPGSQDI
     NVERVETLKQ AIRSGQLTMD TGKIADALLK NVADDLKNS