ID   FLHA_PROMI              Reviewed;         696 AA.
AC   Q51910;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Flagellar biosynthesis protein FlhA;
GN   Name=flhA;
OS   Proteus mirabilis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Proteus.
OX   NCBI_TaxID=584;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=U6450;
RX   PubMed=7783646; DOI=10.1111/j.1365-2958.1995.tb02383.x;
RA   Gygi D., Bailey M.J., Allison C., Hughes C.;
RT   "Requirement for FlhA in flagella assembly and swarm-cell differentiation
RT   by Proteus mirabilis.";
RL   Mol. Microbiol. 15:761-769(1995).
CC   -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC       apparatus. Together with FliI and FliH, may constitute the export
CC       apparatus of flagellin (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC       pore) family. {ECO:0000305}.
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DR   EMBL; L36848; AAA50309.1; -; Genomic_DNA.
DR   PIR; S61502; S61502.
DR   RefSeq; WP_041701178.1; NZ_VKHV01000013.1.
DR   AlphaFoldDB; Q51910; -.
DR   SMR; Q51910; -.
DR   STRING; 584.AOUC001_07275; -.
DR   PATRIC; fig|584.86.peg.1842; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 1.10.8.540; -; 1.
DR   Gene3D; 3.40.30.60; -; 1.
DR   Gene3D; 3.40.50.12790; -; 1.
DR   InterPro; IPR042194; FHIPEP_1.
DR   InterPro; IPR042193; FHIPEP_3.
DR   InterPro; IPR042196; FHIPEP_4.
DR   InterPro; IPR025505; FHIPEP_CS.
DR   InterPro; IPR006301; FlhA.
DR   InterPro; IPR001712; T3SS_FHIPEP.
DR   PANTHER; PTHR30161; PTHR30161; 1.
DR   Pfam; PF00771; FHIPEP; 1.
DR   PIRSF; PIRSF005419; FlhA; 1.
DR   PRINTS; PR00949; TYPE3IMAPROT.
DR   TIGRFAMs; TIGR01398; FlhA; 1.
DR   PROSITE; PS00994; FHIPEP; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Bacterial flagellum protein export;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..696
FT                   /note="Flagellar biosynthesis protein FlhA"
FT                   /id="PRO_0000190020"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        478..498
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   696 AA;  76145 MW;  75E587E1BB4B6AFD CRC64;
     MANLASLLRL PGNWKSSQWQ ILAGPVLILL ILSMMVLPLP PFLLDLLFTF NIALSIMVLL
     VAMFTRRTLD FAAFPTILLF TTLLRLSLNV ASTRIILMEG HTGSAAAGRV VEAFGHFLVG
     GNFAIGIVVF IILILINFMV ITKGAGRIAE VGARFVLDGM PGKQMAIDAD LNAGIINEEE
     AKKRRKEVSL ESDFYGSMDG ASKFVRGDAI AGLMILVINV VGGLVVGVAQ HNMALNDAAS
     TYTLLTIGDG LVAQIPALII STAAGVIVTR VATDEDVGQQ MVTQLFDNPR VLMLTAGVLG
     LLGLVPGMPN FVFLFFTAAL AGLGWYILKR HSSPQVQQQK ELEQVEKQNR VVEASWEDVQ
     LEDPLSMEVG YRLIPMVDNR QNGELLGRIS GIRKKFAQEM GYLPPVVHIR DNMEVKPSSY
     RILMKGVEIG HGEAHPGRWL AINPGNAVGT LEGDNTQEPA FGLPAVWIDD SLREQAQVQG
     YTVVAASTVI ATHFNHVLNQ YAAELFGRQE AQMLFDRVSK ELPKMTENMI PDMLSLTVLH
     KVLQNLLAEQ VPIRDMRTIL EALAEHAPEQ KDPAELTAVV RVALRRAITQ HWFGDKEEIQ
     VIGLDAGLER LLLQAMQSGG GLEPGLAENI EQQALDAVRR QEMSGGVPVL LVNHALRSLL
     SRFLRRSLPQ LAVLSNMEIS EGRHIRMTSM IGGQNN