ID   FLHA_YEREN              Reviewed;         692 AA.
AC   Q56887;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Flagellar biosynthesis protein FlhA;
GN   Name=flhA;
OS   Yersinia enterocolitica.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=630;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=W1024 / Serotype O:9;
RX   PubMed=9387224; DOI=10.1099/00221287-143-11-3461;
RA   Fauconnier A., Allaoui A., Campos A., van Elsen A., Cornelis G.R.,
RA   Bollen A.;
RT   "Flagellar flhA, flhB and flhE genes, organized in an operon, cluster
RT   upstream from the inv locus in Yersinia enterocolitica.";
RL   Microbiology 143:3461-3471(1997).
CC   -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC       apparatus. Together with FliI and FliH, may constitute the export
CC       apparatus of flagellin (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC       pore) family. {ECO:0000305}.
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DR   EMBL; Z48169; CAA88186.1; -; Genomic_DNA.
DR   PIR; S54214; S54214.
DR   RefSeq; WP_005164472.1; NZ_LR698980.1.
DR   AlphaFoldDB; Q56887; -.
DR   SMR; Q56887; -.
DR   STRING; 1443113.LC20_02147; -.
DR   PRIDE; Q56887; -.
DR   eggNOG; COG1298; Bacteria.
DR   OMA; MAINPGQ; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 1.10.8.540; -; 1.
DR   Gene3D; 3.40.30.60; -; 1.
DR   Gene3D; 3.40.50.12790; -; 1.
DR   InterPro; IPR042194; FHIPEP_1.
DR   InterPro; IPR042193; FHIPEP_3.
DR   InterPro; IPR042196; FHIPEP_4.
DR   InterPro; IPR025505; FHIPEP_CS.
DR   InterPro; IPR006301; FlhA.
DR   InterPro; IPR001712; T3SS_FHIPEP.
DR   PANTHER; PTHR30161; PTHR30161; 1.
DR   Pfam; PF00771; FHIPEP; 1.
DR   PIRSF; PIRSF005419; FlhA; 1.
DR   PRINTS; PR00949; TYPE3IMAPROT.
DR   TIGRFAMs; TIGR01398; FlhA; 1.
DR   PROSITE; PS00994; FHIPEP; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Bacterial flagellum protein export;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..692
FT                   /note="Flagellar biosynthesis protein FlhA"
FT                   /id="PRO_0000190022"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        296..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        446..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   692 AA;  74967 MW;  E9785C6E7452DE90 CRC64;
     MANLAALLRL PGNFKDTQWQ ILAGPILILM ILSMMVLPLP PFILDLLFTF NIALSIMVLL
     VAMFTQRTLD FAAFPTILLF STLLRLSLNV ASTRIILMDG HTGAAAAGRV VEAFGHFLVG
     GNFAIGIVVF VILVIINFMV ITKGAGRIAE VGARFVLDGM PGKQMAIDAD LNAGLIGEDE
     AKKRRSDVTQ EADFYGSMDG ASKFVRGDAV AGLLIMVINV VGGLLVGVLQ HNMAVGHAAE
     TYTLLTIGDG LVAQIPALVI STAAGVIVTR VSTDQDVGQQ MVTQLFNNPR VMVLSAAVLG
     LLGMVPGMPN FVFLLFTAAL LALAWRLRGK QSQQPTAAEA PVIQDQQQAT EATWSDVQLE
     DPLGMEVGYR LIPMVDFQQN GELLGRIRSI RKKFAQEMGY LPPVVHIRDN LELPPASYRI
     LMKGVEIGSG EAHPGRWLAI NPGNAVGTLP GEATQDPAFG LAAVWIESAL REQAQIQGFT
     VVEASTVVAT HLNHLISQYA SDLFGRQETQ QLLDRVSQEM PKLTEDFIPG VVTLTTLHKV
     LQNLLMERVS IRDMRTIIET LAEHAPNQTD PYELTAVVRV ALGRSIAQQW FPGTGEIQVI
     GLDAALERLL LQALQGGSGL EPGLADRLLE QSRQALQRQE MLGAPPVLLV NHALRALLAR
     FLRRSLPQMV VLSNLEIGDN RQIRMTSTIG VA