ID   FLHB_AQUAE              Reviewed;         350 AA.
AC   O67813;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Flagellar biosynthetic protein FlhB;
GN   Name=flhB; OrderedLocusNames=aq_2014;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Required for formation of the rod structure in the basal body
CC       of the flagellar apparatus. Together with FliI and FliH, may constitute
CC       the export apparatus of flagellin (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC       {ECO:0000305}.
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DR   EMBL; AE000657; AAC07777.1; -; Genomic_DNA.
DR   PIR; A70473; A70473.
DR   RefSeq; NP_214382.1; NC_000918.1.
DR   RefSeq; WP_010881318.1; NC_000918.1.
DR   PDB; 3B1S; X-ray; 2.55 A; A/C/E=213-263, B/D/F=264-350.
DR   PDBsum; 3B1S; -.
DR   AlphaFoldDB; O67813; -.
DR   SMR; O67813; -.
DR   STRING; 224324.aq_2014; -.
DR   MEROPS; N06.A01; -.
DR   PRIDE; O67813; -.
DR   EnsemblBacteria; AAC07777; AAC07777; aq_2014.
DR   KEGG; aae:aq_2014; -.
DR   PATRIC; fig|224324.8.peg.1557; -.
DR   eggNOG; COG1377; Bacteria.
DR   HOGENOM; CLU_041013_1_2_0; -.
DR   InParanoid; O67813; -.
DR   OMA; DEYKQQE; -.
DR   OrthoDB; 1424100at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 3.40.1690.10; -; 1.
DR   InterPro; IPR006136; FlhB.
DR   InterPro; IPR006135; T3SS_substrate_exporter.
DR   InterPro; IPR029025; T3SS_substrate_exporter_C.
DR   PANTHER; PTHR30531; PTHR30531; 1.
DR   Pfam; PF01312; Bac_export_2; 1.
DR   PRINTS; PR00950; TYPE3IMSPROT.
DR   SUPFAM; SSF160544; SSF160544; 1.
DR   TIGRFAMs; TIGR00328; flhB; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Bacterial flagellum biogenesis;
KW   Bacterial flagellum protein export; Cell inner membrane; Cell membrane;
KW   Membrane; Protein transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..350
FT                   /note="Flagellar biosynthetic protein FlhB"
FT                   /id="PRO_0000180943"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   HELIX           233..252
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   HELIX           254..256
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   STRAND          258..262
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   STRAND          267..272
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   TURN            275..277
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   STRAND          282..288
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   HELIX           290..302
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   STRAND          306..308
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   HELIX           310..316
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   TURN            317..319
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   HELIX           328..330
FT                   /evidence="ECO:0007829|PDB:3B1S"
FT   HELIX           331..347
FT                   /evidence="ECO:0007829|PDB:3B1S"
SQ   SEQUENCE   350 AA;  39715 MW;  5F828280BA81EDC3 CRC64;
     MAEEHKTERA TPYKRRKVRE EGNVAKSHEI ASSLVVLLSL LLLLFLGTYI AKEVILIFLA
     VTGYVHADIS ELGSLYENFY ENIVKVLTPL FFLALLVVIL SHVAQFGFIF TLKPLSFKWE
     RINPFEGIKR LISLTTLFET VKNTLKAFLL IGIAVFVLKG SLYFFLSSST YPLAETLKSF
     IKTSAITLIT LGVVALLIAF LDYAFKRWQY EKKIMMSRRE LKEEYKQLEG HPEVKSRIKA
     RMRELAKSRM MAEVPKATVV ITNPTHIAIA LKYNPEKDKA PVVVAKGKGT IAQKIVEIAE
     NYSIPVVRKP ELARALYPAV EVGKEISPKF YKAVAEIIAY VMFKKKKVYA