FLHB_BACSU
ID FLHB_BACSU Reviewed; 360 AA.
AC P35538; O31746;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Flagellar biosynthetic protein FlhB;
GN Name=flhB; OrderedLocusNames=BSU16380;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / OI1085;
RX PubMed=8299954; DOI=10.1016/0378-1119(93)90014-t;
RA Carpenter P.B., Zuberi A.R., Ordal G.W.;
RT "Bacillus subtilis flagellar proteins FliP, FliQ, FliR and FlhB are related
RT to Shigella flexneri virulence factors.";
RL Gene 137:243-245(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- FUNCTION: May be involved in the export of flagellum proteins.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC {ECO:0000305}.
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DR EMBL; X74121; CAA52218.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB13511.1; -; Genomic_DNA.
DR PIR; D69623; D69623.
DR RefSeq; NP_389520.1; NC_000964.3.
DR RefSeq; WP_003231949.1; NZ_JNCM01000035.1.
DR AlphaFoldDB; P35538; -.
DR SMR; P35538; -.
DR STRING; 224308.BSU16380; -.
DR PaxDb; P35538; -.
DR PRIDE; P35538; -.
DR EnsemblBacteria; CAB13511; CAB13511; BSU_16380.
DR GeneID; 940128; -.
DR KEGG; bsu:BSU16380; -.
DR PATRIC; fig|224308.179.peg.1779; -.
DR eggNOG; COG1377; Bacteria.
DR InParanoid; P35538; -.
DR OMA; DEYKQQE; -.
DR PhylomeDB; P35538; -.
DR BioCyc; BSUB:BSU16380-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IMP:CACAO.
DR GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IMP:CACAO.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.1690.10; -; 1.
DR InterPro; IPR006136; FlhB.
DR InterPro; IPR006135; T3SS_substrate_exporter.
DR InterPro; IPR029025; T3SS_substrate_exporter_C.
DR PANTHER; PTHR30531; PTHR30531; 1.
DR Pfam; PF01312; Bac_export_2; 1.
DR PRINTS; PR00950; TYPE3IMSPROT.
DR SUPFAM; SSF160544; SSF160544; 1.
DR TIGRFAMs; TIGR00328; flhB; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis; Bacterial flagellum protein export;
KW Cell membrane; Membrane; Protein transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..360
FT /note="Flagellar biosynthetic protein FlhB"
FT /id="PRO_0000180944"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 40
FT /note="T -> S (in Ref. 1; CAA52218)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 360 AA; 41097 MW; 1E157D9B52B2379C CRC64;
MKLRVDLQFF AGEKTEKATP KKRKDTRKKG QVAKSSDVNT AVSLLVIFLS LIAIGPYMRD
RLLSFIETFY TESLTMKLSE SNVHTLFVSL LKDMGMILAP ILLVALVAGV VSNYMQVGFL
FSAEVIQPKL EKLDPIKGFK RIYSMRAIVE LIKSILKIVV VGFAAFAVLW LHYGEILRLP
LLTPEEALSF VSKLTLWMGL SGAGALLILA GLDYLYQRFD YEKNIKMSKQ DIKDEYKKSE
GDPIIKSKIK QRQREMAMRR MMQEVPKADV IITNPTHYAI ALKYDEEKMD APYIVAKGVD
HLALKIRKIA KEHDVMMVEN RPLARALYDQ VEIDQAVPEE FFKVLAEILA YVYKTKQKVY