ID   FLHB_BORBU              Reviewed;         372 AA.
AC   Q44760; Q44908;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 123.
DE   RecName: Full=Flagellar biosynthetic protein FlhB;
GN   Name=flhB; OrderedLocusNames=BB_0272;
OS   Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS   (Borrelia burgdorferi).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=224326;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RA   Dunn J.J., Butler-Loffredo L., Kieleczawa J., Medalle J., Luft B.J.;
RL   Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=212;
RA   Ge Y., Charon N.W.;
RL   Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA   Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA   Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA   van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA   Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA   Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA   Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL   Nature 390:580-586(1997).
CC   -!- FUNCTION: Required for formation of the rod structure in the basal body
CC       of the flagellar apparatus. Together with FliI and FliH, may constitute
CC       the export apparatus of flagellin (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC       {ECO:0000305}.
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DR   EMBL; U43739; AAA85596.1; -; Genomic_DNA.
DR   EMBL; L75945; AAB58971.1; -; Genomic_DNA.
DR   EMBL; AE000783; AAC66676.1; -; Genomic_DNA.
DR   PIR; H70133; H70133.
DR   RefSeq; NP_212406.1; NC_001318.1.
DR   RefSeq; WP_002657716.1; NC_001318.1.
DR   AlphaFoldDB; Q44760; -.
DR   SMR; Q44760; -.
DR   STRING; 224326.BB_0272; -.
DR   MEROPS; N06.A01; -.
DR   PRIDE; Q44760; -.
DR   EnsemblBacteria; AAC66676; AAC66676; BB_0272.
DR   GeneID; 56567703; -.
DR   KEGG; bbu:BB_0272; -.
DR   PATRIC; fig|224326.49.peg.671; -.
DR   HOGENOM; CLU_041013_1_2_12; -.
DR   OMA; DEYKQQE; -.
DR   Proteomes; UP000001807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 3.40.1690.10; -; 1.
DR   InterPro; IPR006136; FlhB.
DR   InterPro; IPR006135; T3SS_substrate_exporter.
DR   InterPro; IPR029025; T3SS_substrate_exporter_C.
DR   PANTHER; PTHR30531; PTHR30531; 1.
DR   Pfam; PF01312; Bac_export_2; 1.
DR   PRINTS; PR00950; TYPE3IMSPROT.
DR   SUPFAM; SSF160544; SSF160544; 1.
DR   TIGRFAMs; TIGR00328; flhB; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Bacterial flagellum protein export;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..372
FT                   /note="Flagellar biosynthetic protein FlhB"
FT                   /id="PRO_0000180945"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        38
FT                   /note="R -> S (in Ref. 2; AAB58971)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   372 AA;  43253 MW;  39171FACB08E64D2 CRC64;
     MIKDEFLIKS WYIPLDFFSA DDEGRTELPT DQKKQKAREE GRVLKSTEIN TAVSLLLLFA
     LFFFMLSYFA LDLIAVFKEQ AIKLPEVMRM SVYTMGFAYI RSIMGYVVLF FFASLAVNFF
     VNIIQVGFFI TFKSLEPRWD KISFNFSRWA KNSFFSAGAF FNLFKSLLKV VIICLIYYFI
     IENNIGKISK LSEYTLQSGI SIVLVIAYKI CFFSVMFLAI VGVFDYLFQR SQYIESLKMT
     KEEVKQERKE MEGDPLLRSR IKERMRVILS TNLRVAIPQA DVVITNPEHF AVAIKWDSET
     MLAPKVLAKG QDEIALTIKK IARENNVPLM ENKLLARALY ANVKVNEEIP REYWEIVSKI
     LVRVYSITKK FN