FLHB_HELPJ
ID FLHB_HELPJ Reviewed; 358 AA.
AC Q9ZL73;
DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 121.
DE RecName: Full=Flagellar biosynthetic protein FlhB;
GN Name=flhB; OrderedLocusNames=jhp_0707;
OS Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=85963;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J99 / ATCC 700824;
RX PubMed=9923682; DOI=10.1038/16495;
RA Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT "Genomic sequence comparison of two unrelated isolates of the human gastric
RT pathogen Helicobacter pylori.";
RL Nature 397:176-180(1999).
CC -!- FUNCTION: Required for formation of the rod structure in the basal body
CC of the flagellar apparatus. Together with FliI and FliH, may constitute
CC the export apparatus of flagellin (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC {ECO:0000305}.
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DR EMBL; AE001439; AAD06292.1; -; Genomic_DNA.
DR PIR; F71897; F71897.
DR RefSeq; WP_000796831.1; NZ_CP011330.1.
DR AlphaFoldDB; Q9ZL73; -.
DR SMR; Q9ZL73; -.
DR STRING; 85963.jhp_0707; -.
DR MEROPS; N06.A01; -.
DR EnsemblBacteria; AAD06292; AAD06292; jhp_0707.
DR KEGG; hpj:jhp_0707; -.
DR PATRIC; fig|85963.30.peg.270; -.
DR eggNOG; COG1377; Bacteria.
DR OMA; DEYKQQE; -.
DR Proteomes; UP000000804; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.1690.10; -; 1.
DR InterPro; IPR006136; FlhB.
DR InterPro; IPR006135; T3SS_substrate_exporter.
DR InterPro; IPR029025; T3SS_substrate_exporter_C.
DR PANTHER; PTHR30531; PTHR30531; 1.
DR Pfam; PF01312; Bac_export_2; 1.
DR PRINTS; PR00950; TYPE3IMSPROT.
DR SUPFAM; SSF160544; SSF160544; 1.
DR TIGRFAMs; TIGR00328; flhB; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis; Bacterial flagellum protein export;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..358
FT /note="Flagellar biosynthetic protein FlhB"
FT /id="PRO_0000180952"
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 358 AA; 41132 MW; 97746E6B5CA0BD38 CRC64;
MAEEEKTELP SAKKIQKARE EGNVPKSMEV VGFLGLLAGL MSIFVFFIWW VDGFSEMYRH
VLKDFSLDFS KESVQELFNQ LAKDTFLLLL PVLIILMVVA FLSNVLQFGW LFAPKVIEPK
FSKINPINGV KNLFSLKKIL DGSLITLKVF LAFFLGFFIF SLFLGELNHA ALLNLQGQLL
WFKSKALWLI SSLLFLFFVL AFVDLIIKRR QYTNSLKMTK QEVKDEYKQQ EGNPEIKAKI
RQMMVKNATN KMMQEIPKSN VVVTNPTHYA VALKFDEEHP VPVVVAKGTD YLAIRIKGIA
REHDIEIIEN KTLARELYRD VKLNATIPEE LFEAVAIVFA QVAKLEQERQ KQKIIKPL
