FLHB_HELPY
ID FLHB_HELPY Reviewed; 358 AA.
AC P56416;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 15-JUL-1998, sequence version 1.
DT 25-MAY-2022, entry version 118.
DE RecName: Full=Flagellar biosynthetic protein FlhB;
GN Name=flhB; OrderedLocusNames=HP_0770;
OS Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=85962;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700392 / 26695;
RX PubMed=9252185; DOI=10.1038/41483;
RA Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT "The complete genome sequence of the gastric pathogen Helicobacter
RT pylori.";
RL Nature 388:539-547(1997).
CC -!- FUNCTION: Required for formation of the rod structure in the basal body
CC of the flagellar apparatus. Together with FliI and FliH, may constitute
CC the export apparatus of flagellin (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC {ECO:0000305}.
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DR EMBL; AE000511; AAD07819.1; -; Genomic_DNA.
DR PIR; B64616; B64616.
DR RefSeq; NP_207563.1; NC_000915.1.
DR RefSeq; WP_000796857.1; NC_018939.1.
DR AlphaFoldDB; P56416; -.
DR SMR; P56416; -.
DR DIP; DIP-3472N; -.
DR IntAct; P56416; 9.
DR MINT; P56416; -.
DR STRING; 85962.C694_03955; -.
DR PaxDb; P56416; -.
DR EnsemblBacteria; AAD07819; AAD07819; HP_0770.
DR KEGG; hpy:HP_0770; -.
DR PATRIC; fig|85962.47.peg.822; -.
DR eggNOG; COG1377; Bacteria.
DR OMA; DEYKQQE; -.
DR PhylomeDB; P56416; -.
DR Proteomes; UP000000429; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.1690.10; -; 1.
DR InterPro; IPR006136; FlhB.
DR InterPro; IPR006135; T3SS_substrate_exporter.
DR InterPro; IPR029025; T3SS_substrate_exporter_C.
DR PANTHER; PTHR30531; PTHR30531; 1.
DR Pfam; PF01312; Bac_export_2; 1.
DR PRINTS; PR00950; TYPE3IMSPROT.
DR SUPFAM; SSF160544; SSF160544; 1.
DR TIGRFAMs; TIGR00328; flhB; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis; Bacterial flagellum protein export;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..358
FT /note="Flagellar biosynthetic protein FlhB"
FT /id="PRO_0000180951"
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 358 AA; 41015 MW; 7A58F094A6723747 CRC64;
MAEEEKTELP SAKKIQKARE EGNVPKSMEV VGVLGLLAGL ISIFVFFIWW VDGFSEMYRH
VLKDFSLDFS KESVQELFNQ LAKDTFLLLL PILIILVVVA FLSNVLQFGW LFAPKVIEPK
FSKINPINGV KNLFSLKKLL DGSLITLKVF LAFFLGFFIF SLFLGELNHA ALLNLQGQLL
WFKNKALWLI SSLLFLFFVL AFIDLAIKRR QYTNSLKMTK QEVKDEYKQQ EGNPEIKAKI
RQMMLKNATN KMMQEIPKAN VVVTNPTHYA VALKFDEEHP VPVVVAKGTD YLAIRIKGIA
REHDIEIIEN KTLARELYRD VKLNAAIPEE LFEAVAIVFA QVAKLEQERQ KQKIIKPL