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FLHB_HELPY
ID   FLHB_HELPY              Reviewed;         358 AA.
AC   P56416;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 1.
DT   25-MAY-2022, entry version 118.
DE   RecName: Full=Flagellar biosynthetic protein FlhB;
GN   Name=flhB; OrderedLocusNames=HP_0770;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Required for formation of the rod structure in the basal body
CC       of the flagellar apparatus. Together with FliI and FliH, may constitute
CC       the export apparatus of flagellin (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC       {ECO:0000305}.
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DR   EMBL; AE000511; AAD07819.1; -; Genomic_DNA.
DR   PIR; B64616; B64616.
DR   RefSeq; NP_207563.1; NC_000915.1.
DR   RefSeq; WP_000796857.1; NC_018939.1.
DR   AlphaFoldDB; P56416; -.
DR   SMR; P56416; -.
DR   DIP; DIP-3472N; -.
DR   IntAct; P56416; 9.
DR   MINT; P56416; -.
DR   STRING; 85962.C694_03955; -.
DR   PaxDb; P56416; -.
DR   EnsemblBacteria; AAD07819; AAD07819; HP_0770.
DR   KEGG; hpy:HP_0770; -.
DR   PATRIC; fig|85962.47.peg.822; -.
DR   eggNOG; COG1377; Bacteria.
DR   OMA; DEYKQQE; -.
DR   PhylomeDB; P56416; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 3.40.1690.10; -; 1.
DR   InterPro; IPR006136; FlhB.
DR   InterPro; IPR006135; T3SS_substrate_exporter.
DR   InterPro; IPR029025; T3SS_substrate_exporter_C.
DR   PANTHER; PTHR30531; PTHR30531; 1.
DR   Pfam; PF01312; Bac_export_2; 1.
DR   PRINTS; PR00950; TYPE3IMSPROT.
DR   SUPFAM; SSF160544; SSF160544; 1.
DR   TIGRFAMs; TIGR00328; flhB; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Bacterial flagellum protein export;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..358
FT                   /note="Flagellar biosynthetic protein FlhB"
FT                   /id="PRO_0000180951"
FT   TRANSMEM        31..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   358 AA;  41015 MW;  7A58F094A6723747 CRC64;
     MAEEEKTELP SAKKIQKARE EGNVPKSMEV VGVLGLLAGL ISIFVFFIWW VDGFSEMYRH
     VLKDFSLDFS KESVQELFNQ LAKDTFLLLL PILIILVVVA FLSNVLQFGW LFAPKVIEPK
     FSKINPINGV KNLFSLKKLL DGSLITLKVF LAFFLGFFIF SLFLGELNHA ALLNLQGQLL
     WFKNKALWLI SSLLFLFFVL AFIDLAIKRR QYTNSLKMTK QEVKDEYKQQ EGNPEIKAKI
     RQMMLKNATN KMMQEIPKAN VVVTNPTHYA VALKFDEEHP VPVVVAKGTD YLAIRIKGIA
     REHDIEIIEN KTLARELYRD VKLNAAIPEE LFEAVAIVFA QVAKLEQERQ KQKIIKPL
 
 
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