FLHB_RHIME
ID FLHB_RHIME Reviewed; 360 AA.
AC O54243;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 24-OCT-2001, sequence version 2.
DT 25-MAY-2022, entry version 114.
DE RecName: Full=Flagellar biosynthetic protein FlhB;
GN Name=flhB; OrderedLocusNames=R00650; ORFNames=SMc03018;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=RU11/001;
RX PubMed=9858749; DOI=10.1016/s0378-1119(98)00160-7;
RA Sourjik V., Sterr W., Platzer J., Bos I., Haslbeck M., Schmitt R.;
RT "Mapping of 41 chemotaxis, flagellar and motility genes to a single region
RT of the Sinorhizobium meliloti chromosome.";
RL Gene 223:283-290(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: Required for formation of the rod structure in the basal body
CC of the flagellar apparatus. Together with FliI and FliH, may constitute
CC the export apparatus of flagellin (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the type III secretion exporter family.
CC {ECO:0000305}.
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DR EMBL; AJ224445; CAA11951.1; -; Genomic_DNA.
DR EMBL; AL591688; CAC45222.1; -; Genomic_DNA.
DR RefSeq; NP_384756.1; NC_003047.1.
DR RefSeq; WP_010968725.1; NC_003047.1.
DR AlphaFoldDB; O54243; -.
DR SMR; O54243; -.
DR STRING; 266834.SMc03018; -.
DR MEROPS; N06.A01; -.
DR EnsemblBacteria; CAC45222; CAC45222; SMc03018.
DR GeneID; 61602117; -.
DR KEGG; sme:SMc03018; -.
DR PATRIC; fig|266834.11.peg.2023; -.
DR eggNOG; COG1377; Bacteria.
DR HOGENOM; CLU_041013_1_2_5; -.
DR OMA; DEYKQQE; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.1690.10; -; 1.
DR InterPro; IPR006136; FlhB.
DR InterPro; IPR006135; T3SS_substrate_exporter.
DR InterPro; IPR029025; T3SS_substrate_exporter_C.
DR PANTHER; PTHR30531; PTHR30531; 1.
DR Pfam; PF01312; Bac_export_2; 1.
DR PRINTS; PR00950; TYPE3IMSPROT.
DR SUPFAM; SSF160544; SSF160544; 1.
DR TIGRFAMs; TIGR00328; flhB; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis; Bacterial flagellum protein export;
KW Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..360
FT /note="Flagellar biosynthetic protein FlhB"
FT /id="PRO_0000180953"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 194..214
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 99
FT /note="F -> S (in Ref. 1; CAA11951)"
FT /evidence="ECO:0000305"
FT CONFLICT 193
FT /note="K -> Q (in Ref. 1; CAA11951)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 360 AA; 40468 MW; CDAD3ED36113991C CRC64;
MAEEQDKDSK TEAPSEKKIS DATEKGNVPF SREVTAFAST LAIYIFVVFF LSDGAANMAE
ALKDIFEQPE AWRLDTATDA VALISHVVLK CAALVLPVFI LLILFGVGSS IFQNLPRPVL
DRIQPKWNRV SPAAGFKRIY GVQGLVEFGK SLFKIIVVSI VVVLVLWNDY FATLDMMFSD
PVTIFTTMIS DLKQIIIVVL FATATLAIVD LFWTRHHWYT ELRMTRQEVK DELKQSQGDP
IVKSRLRSMQ RDRARKRMIS SVPRATLIIA NPTHYAVALR YVREESDAPV VVAMGKDLVA
LKIREIAEKN GIPVFEDPPL ARSMFAQVSV DSVIPPVFYK AVAELIHRVY AAQPQQRRVT
