ID   AKTP1_DROGR             Reviewed;         246 AA.
AC   B4J613;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Protein crossbronx;
GN   Name=cbx; ORFNames=GH20212;
OS   Drosophila grimshawi (Hawaiian fruit fly) (Idiomyia grimshawi).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Hawaiian Drosophila.
OX   NCBI_TaxID=7222;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15287-2541.00;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. FTS
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU00388}.
CC   -!- CAUTION: Lacks the conserved Cys residue necessary for ubiquitin-
CC       conjugating enzyme E2 activity. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH916367; EDW01871.1; -; Genomic_DNA.
DR   RefSeq; XP_001987004.1; XM_001986968.1.
DR   AlphaFoldDB; B4J613; -.
DR   SMR; B4J613; -.
DR   STRING; 7222.FBpp0154118; -.
DR   PRIDE; B4J613; -.
DR   EnsemblMetazoa; FBtr0155626; FBpp0154118; FBgn0127676.
DR   GeneID; 6560741; -.
DR   KEGG; dgr:6560741; -.
DR   eggNOG; KOG0429; Eukaryota.
DR   HOGENOM; CLU_083049_1_0_1; -.
DR   InParanoid; B4J613; -.
DR   OMA; QVLKYMQ; -.
DR   OrthoDB; 1226125at2759; -.
DR   PhylomeDB; B4J613; -.
DR   ChiTaRS; Ubx; fly.
DR   Proteomes; UP000001070; Unassembled WGS sequence.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   Pfam; PF00179; UQ_con; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
DR   PROSITE; PS50127; UBC_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..246
FT                   /note="Protein crossbronx"
FT                   /id="PRO_0000379031"
FT   DOMAIN          20..177
FT                   /note="UBC core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00388"
SQ   SEQUENCE   246 AA;  28091 MW;  ABC82CC2EC1E0C33 CRC64;
     MTLDLDAQKK DEKLLLATIQ QEYKILAEYK MIESEKLSGI YVIPSYANSL QWFGVFFGRH
     GFYEKSVFRF SILLSDGFPD DKSVPAIVFQ HNVVHPLVCP YTYSLDLSHA FHEWRPAEDH
     LWQVLKYMQA IFADPLESIR NVSTVHERSN AEIIKLLNNN RDAYAALVQE SILESKAHIY
     DNPHTEDPHY IIFEKFQDDI HGPVLEQIRQ NRATVGSTES GGGGGAATGL SWVKFKEGEF
     KPLSIE