ID   FLHC_PARAM              Reviewed;         216 AA.
AC   D5W6H7;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   13-JUL-2010, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Flagellar transcriptional regulator FlhC {ECO:0000255|HAMAP-Rule:MF_01891};
GN   Name=flhC {ECO:0000255|HAMAP-Rule:MF_01891}; OrderedLocusNames=BC1002_3053;
OS   Paraburkholderia atlantica.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=2654982;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCGE1002;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA   Kyrpides N., Ovchinnikova G., Martinez-Romero E., Hernandez M.A.R.,
RA   Tiedje J.M., Woyke T.;
RT   "Complete sequence of chromosome 1 of Burkholderia sp. CCGE1002.";
RL   Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Functions in complex with FlhD as a master transcriptional
CC       regulator that regulates transcription of several flagellar and non-
CC       flagellar operons by binding to their promoter region. Activates
CC       expression of class 2 flagellar genes, including fliA, which is a
CC       flagellum-specific sigma factor that turns on the class 3 genes. Also
CC       regulates genes whose products function in a variety of physiological
CC       pathways. {ECO:0000255|HAMAP-Rule:MF_01891}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01891};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000255|HAMAP-Rule:MF_01891};
CC   -!- SUBUNIT: Heterohexamer composed of two FlhC and four FlhD subunits.
CC       Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer
CC       assembles by dimerization of two heterotrimers. {ECO:0000255|HAMAP-
CC       Rule:MF_01891}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01891}.
CC   -!- SIMILARITY: Belongs to the FlhC family. {ECO:0000255|HAMAP-
CC       Rule:MF_01891}.
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DR   EMBL; CP002013; ADG17098.1; -; Genomic_DNA.
DR   RefSeq; WP_013090905.1; NC_014117.1.
DR   AlphaFoldDB; D5W6H7; -.
DR   SMR; D5W6H7; -.
DR   STRING; 640511.BC1002_3053; -.
DR   EnsemblBacteria; ADG17098; ADG17098; BC1002_3053.
DR   KEGG; bge:BC1002_3053; -.
DR   eggNOG; ENOG502Z927; Bacteria.
DR   HOGENOM; CLU_122824_0_0_4; -.
DR   OrthoDB; 1247512at2; -.
DR   Proteomes; UP000002190; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:1902208; P:regulation of bacterial-type flagellum assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01891; FhlC; 1.
DR   InterPro; IPR007944; FlhC.
DR   Pfam; PF05280; FlhC; 1.
DR   PIRSF; PIRSF003159; FlhC; 1.
PE   3: Inferred from homology;
KW   Activator; Bacterial flagellum biogenesis; Cytoplasm; DNA-binding;
KW   Metal-binding; Transcription; Transcription regulation; Zinc.
FT   CHAIN           1..216
FT                   /note="Flagellar transcriptional regulator FlhC"
FT                   /id="PRO_0000406757"
FT   BINDING         137
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01891"
FT   BINDING         140
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01891"
FT   BINDING         157
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01891"
FT   BINDING         160
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01891"
SQ   SEQUENCE   216 AA;  24117 MW;  69AAC9DAA1ABF549 CRC64;
     MASKSVVLEA REITLAIELI ELGARLQLLE AETSLSRDRL VKLYKELKGV SPPKGMLPFS
     TDWFMTWQPN FHSSLFYNIY RFMAGHGGCR AIESIVKSYR LYLEHVQLQD DEPVLSLTRA
     WTLVRFFDSG MLQLSVCRRC GGQFVAHAHD PQHAFVCGLC QPPSRAGKTK KAAQTRPERQ
     SAVAGIPAEV PQVAEARAHE ARCTAPTLDT FVTAEV