ID   AKTP1_DROPS             Reviewed;         244 AA.
AC   Q28XA5;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Protein crossbronx;
GN   Name=cbx; ORFNames=GA10380;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. FTS
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU00388}.
CC   -!- CAUTION: Lacks the conserved Cys residue necessary for ubiquitin-
CC       conjugating enzyme E2 activity. {ECO:0000305}.
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DR   EMBL; CM000071; EAL26411.1; -; Genomic_DNA.
DR   RefSeq; XP_001361832.1; XM_001361795.3.
DR   AlphaFoldDB; Q28XA5; -.
DR   SMR; Q28XA5; -.
DR   STRING; 7237.FBpp0275919; -.
DR   EnsemblMetazoa; FBtr0277481; FBpp0275919; FBgn0070437.
DR   GeneID; 4805431; -.
DR   KEGG; dpo:Dpse_GA10380; -.
DR   eggNOG; KOG0429; Eukaryota.
DR   HOGENOM; CLU_083049_1_0_1; -.
DR   InParanoid; Q28XA5; -.
DR   OMA; QVLKYMQ; -.
DR   PhylomeDB; Q28XA5; -.
DR   ChiTaRS; Ubx; fly.
DR   Proteomes; UP000001819; Chromosome 3.
DR   Bgee; FBgn0070437; Expressed in insect adult head and 2 other tissues.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   Pfam; PF00179; UQ_con; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
DR   PROSITE; PS50127; UBC_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..244
FT                   /note="Protein crossbronx"
FT                   /id="PRO_0000379035"
FT   DOMAIN          20..176
FT                   /note="UBC core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00388"
SQ   SEQUENCE   244 AA;  28108 MW;  734D323D1E351909 CRC64;
     MTLDLDANKK DDKILITTIQ QEYKILAEYK MIESEKLGGI YTIPSLANSL QWFGVFFGRQ
     GLYSESVFRF SLLLPDRFPD DKSLPTVIFQ QNILHPHVCP YTNSLDISHA FPEWRCGEDH
     LWQLFKYMQA IFSDPIDSIR GIEMDKIKNP EAAELLLTNR EEFAARVLEN IKESKEHIYD
     PQPTEDPHYI VFEKFQPDVH GPVLERIKAG RNNQTDSTLQ QTNGGTATGL SWVKEGEFKP
     LSIE