ID   AKTP1_DROSE             Reviewed;         244 AA.
AC   B4HT57;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Protein crossbronx;
GN   Name=cbx; ORFNames=GM20572;
OS   Drosophila sechellia (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rob3c / Tucson 14021-0248.25;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. FTS
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU00388}.
CC   -!- CAUTION: Lacks the conserved Cys residue necessary for ubiquitin-
CC       conjugating enzyme E2 activity. {ECO:0000305}.
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DR   EMBL; CH480816; EDW47167.1; -; Genomic_DNA.
DR   RefSeq; XP_002033154.1; XM_002033118.1.
DR   AlphaFoldDB; B4HT57; -.
DR   SMR; B4HT57; -.
DR   STRING; 7238.B4HT57; -.
DR   EnsemblMetazoa; FBtr0203557; FBpp0202049; FBgn0175454.
DR   GeneID; 6608420; -.
DR   KEGG; dse:6608420; -.
DR   HOGENOM; CLU_083049_1_0_1; -.
DR   OMA; QVLKYMQ; -.
DR   PhylomeDB; B4HT57; -.
DR   ChiTaRS; Ubx; fly.
DR   Proteomes; UP000001292; Unassembled WGS sequence.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:EnsemblMetazoa.
DR   GO; GO:0007291; P:sperm individualization; IEA:EnsemblMetazoa.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   Pfam; PF00179; UQ_con; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
DR   PROSITE; PS50127; UBC_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..244
FT                   /note="Protein crossbronx"
FT                   /id="PRO_0000379036"
FT   DOMAIN          20..176
FT                   /note="UBC core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00388"
FT   REGION          209..244
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..227
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   244 AA;  28180 MW;  B86386863882E3A1 CRC64;
     MTLDLDAHKK DDKLLITTIQ QEYKILAEYK MIESEKLSGI YVIPSYANSL QWFGVFFGRQ
     GLYAESVFRF TILLPDRFPD DKSLPTIIFQ QDVIHPHVCP YTHSLDVSHA FPEWRCGEDH
     LWQLLKYLQV IFSDPLDSIR GIEVDKLKNR EAAELLMNNK EEYVARVQEN IKESKEHIFD
     TPPTEDPNYI VFEKFQQDVH GPVLDRIKAG RSKQTEPSAQ QGNGGHATGL SWVKEGEFKP
     LSIE