ID   FLIC_SHIFL              Reviewed;         550 AA.
AC   Q08860;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 131.
DE   RecName: Full=Flagellin;
GN   Name=fliC; OrderedLocusNames=SF1966, S2062;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IID642;
RX   PubMed=8057852; DOI=10.1111/j.1365-2958.1994.tb01016.x;
RA   Tominaga A., Mahmoud M.A.-H., Mukaihara T., Enomoto M.;
RT   "Molecular characterization of intact, but cryptic, flagellin genes in the
RT   genus Shigella.";
RL   Mol. Microbiol. 12:277-285(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC       the filaments of bacterial flagella.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- SIMILARITY: Belongs to the bacterial flagellin family. {ECO:0000305}.
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DR   EMBL; D16819; BAA04093.1; -; Genomic_DNA.
DR   EMBL; AE005674; AAN43516.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP17345.1; -; Genomic_DNA.
DR   PIR; S44980; S44980.
DR   RefSeq; NP_707809.1; NC_004337.2.
DR   RefSeq; WP_000079690.1; NZ_WPGW01000033.1.
DR   AlphaFoldDB; Q08860; -.
DR   SMR; Q08860; -.
DR   STRING; 198214.SF1966; -.
DR   EnsemblBacteria; AAN43516; AAN43516; SF1966.
DR   EnsemblBacteria; AAP17345; AAP17345; S2062.
DR   GeneID; 1025169; -.
DR   GeneID; 58389823; -.
DR   KEGG; sfl:SF1966; -.
DR   KEGG; sfx:S2062; -.
DR   PATRIC; fig|198214.7.peg.2347; -.
DR   HOGENOM; CLU_011142_7_2_6; -.
DR   OMA; IASQTTY; -.
DR   OrthoDB; 636786at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 6.10.10.10; -; 1.
DR   InterPro; IPR001492; Flagellin.
DR   InterPro; IPR046358; Flagellin_C.
DR   InterPro; IPR042187; Flagellin_C_sub2.
DR   InterPro; IPR001029; Flagellin_N.
DR   InterPro; IPR032826; FliC_H7.
DR   PANTHER; PTHR42792; PTHR42792; 1.
DR   Pfam; PF00700; Flagellin_C; 1.
DR   Pfam; PF00669; Flagellin_N; 1.
DR   Pfam; PF12445; FliC; 1.
DR   PRINTS; PR00207; FLAGELLIN.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Reference proteome; Secreted.
FT   CHAIN           1..550
FT                   /note="Flagellin"
FT                   /id="PRO_0000182582"
SQ   SEQUENCE   550 AA;  56637 MW;  CC921C9A8EF200B6 CRC64;
     MAQVINTNSL SLITQNNINK NQSALSSSIE RLSSGLRINS AKDDAAGQAI ANRFTSNIKG
     LTQAARNAND GISVAQTTEG ALSEINNNLQ RIRELTVQAS TGTNSDSDLD SIQDEIKSRL
     DEIDRVSGQT QFNGVNVLAK DGSMKIQVGA NDGQTITIDL KKIDSDTLGL NGFNVNGGGA
     VANTAASKAD LVAANATVVG NKYTVSAGYD AAKASDLLAG VSDGDTVQAT INNGFGTAAS
     ATNYKYDSAS KSYSFDTTTA SAADVQKYLT PGVGDTAKGT ITIDGSAQDV QISSDGKITA
     SNGDKLYIDT TGRLTKNGSG ASLTEASLST LAANNTKATT IDIGGTSISF TGNSTTPDTI
     TYSVTGAKVD QAAFDKAVST SGNNVDFTTA GYSVNGTTGA VTKGVDSVYV DNNEALTTSD
     TVDFYLQDDG SVTNGSGKAV YKDADGKLTT DAETKAATTA DPLKALDEAI SSIDKFRSSL
     GAVQNRLDSA VTNLNNTTTN LSEAQSRIQD ADYATEVSNM SKAQIIQQAG NSVLAKANQV
     PQQVLSLLQG