ID   FLIDL_VIBPA             Reviewed;         445 AA.
AC   Q03475;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2003, sequence version 2.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=Lateral flagellar hook-associated protein 2;
DE            Short=HAP2;
DE   AltName: Full=Filament CAP protein;
DE   AltName: Full=Flagellar cap protein;
GN   Name=fliDL; Synonyms=lafB; OrderedLocusNames=VPA1550;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BB22;
RX   PubMed=8501040; DOI=10.1128/jb.175.11.3361-3371.1993;
RA   McCarter L.L., Wright M.E.;
RT   "Identification of genes encoding components of the swarmer cell flagellar
RT   motor and propeller and a sigma factor controlling differentiation of
RT   Vibrio parahaemolyticus.";
RL   J. Bacteriol. 175:3361-3371(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- FUNCTION: Required for the morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end. Essential for swarming motility.
CC   -!- SUBUNIT: Homopentamer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- MISCELLANEOUS: V.parahaemolyticus possesses two flagellar systems: a
CC       single polar flagellum propels the bacterium in liquid (swimming),
CC       while multiple lateral (peritrichous) flagella move the bacterium over
CC       surfaces (swarming). The polar flagellum is synthesized constitutively
CC       but lateral flagella are produced only under conditions in which the
CC       polar flagellum is not functional.
CC   -!- SIMILARITY: Belongs to the FliD family. {ECO:0000305}.
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DR   EMBL; L06176; AAA27530.1; -; Genomic_DNA.
DR   EMBL; U52957; AAB07351.1; -; Genomic_DNA.
DR   EMBL; BA000032; BAC62893.1; -; Genomic_DNA.
DR   PIR; B40590; B40590.
DR   RefSeq; NP_801060.1; NC_004605.1.
DR   RefSeq; WP_005462779.1; NC_004605.1.
DR   AlphaFoldDB; Q03475; -.
DR   SMR; Q03475; -.
DR   STRING; 223926.28809952; -.
DR   EnsemblBacteria; BAC62893; BAC62893; BAC62893.
DR   GeneID; 1192246; -.
DR   KEGG; vpa:VPA1550; -.
DR   PATRIC; fig|223926.6.peg.4472; -.
DR   eggNOG; COG1345; Bacteria.
DR   HOGENOM; CLU_015182_7_0_6; -.
DR   OMA; DWGMTER; -.
DR   Proteomes; UP000002493; Chromosome 2.
DR   GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR040026; FliD.
DR   InterPro; IPR010809; FliD_C.
DR   InterPro; IPR003481; FliD_N.
DR   PANTHER; PTHR30288; PTHR30288; 1.
DR   Pfam; PF07196; Flagellin_IN; 1.
DR   Pfam; PF07195; FliD_C; 1.
DR   Pfam; PF02465; FliD_N; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Coiled coil; Reference proteome; Secreted.
FT   CHAIN           1..445
FT                   /note="Lateral flagellar hook-associated protein 2"
FT                   /id="PRO_0000177029"
FT   COILED          388..423
FT                   /evidence="ECO:0000255"
FT   CONFLICT        226
FT                   /note="K -> N (in Ref. 1; AAA27530/AAB07351)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   445 AA;  48279 MW;  7B1836FC8722F00A CRC64;
     MSSIDPATFA AQFAQIEIQP FKQRYQLQTN TYQSQLSALG KVESAMREFR TALNEMNSST
     NSIIKNSTSI SQEGYFTANA DAKALSGSYQ IFVEQVATSH QVSTGMPADL DATTEIPKTG
     NLEFTINGKT MTIDLSTVDT DGDGVTTVSD LTKAINNNSD NPGVNATLVR SNGQTHFMLS
     STETGVANQI NVSATGTGQA WFEDAFTNLS QISAPQDAVI WLGAEKTGLK LTNSSNTFEG
     VIDGVDITVT KAQTSGETAI GLGIGADDEA TKEQLNKFVD AYNTLISTID EHTQIGSEDK
     KRGVLASDPT MRSIESQLSS LVRGEHGGMR LSEIGVTLDR HGKLKVDQEK FAEAQKNNSA
     GLEAMFNGDG ALLDSMDAMA EPFLKFSSGA FKSRKEALQA NLDRLSDKQT TLERKYDMSY
     KRYLKQFTQM NTLMTQMNQT MSMFG