ID   FLID_BACSU              Reviewed;         498 AA.
AC   P39738; P96504;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Flagellar hook-associated protein 2;
DE            Short=HAP2;
DE   AltName: Full=Filament cap protein;
DE   AltName: Full=Flagellar cap protein;
GN   Name=fliD; Synonyms=mrgB; OrderedLocusNames=BSU35340;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / HB2058;
RX   PubMed=8195064; DOI=10.1128/jb.176.11.3093-3101.1994;
RA   Chen L., Helmann J.D.;
RT   "The Bacillus subtilis sigma D-dependent operon encoding the flagellar
RT   proteins FliD, FliS, and FliT.";
RL   J. Bacteriol. 176:3093-3101(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=8969505; DOI=10.1099/13500872-142-11-3079;
RA   Soldo B., Lazarevic V., Mauel C., Karamata D.;
RT   "Sequence of the 305 degrees-307 degrees region of the Bacillus subtilis
RT   chromosome.";
RL   Microbiology 142:3079-3088(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Required for the morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homopentamer. {ECO:0000250}.
CC   -!- INTERACTION:
CC       P39738; P39740: fliT; NbExp=2; IntAct=EBI-15858644, EBI-15858561;
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- SIMILARITY: Belongs to the FliD family. {ECO:0000305}.
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DR   EMBL; Z31376; CAA83248.1; -; Genomic_DNA.
DR   EMBL; U56901; AAC44953.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15551.1; -; Genomic_DNA.
DR   PIR; H69623; H69623.
DR   RefSeq; NP_391414.1; NC_000964.3.
DR   RefSeq; WP_003242960.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; P39738; -.
DR   SMR; P39738; -.
DR   DIP; DIP-59542N; -.
DR   IntAct; P39738; 2.
DR   STRING; 224308.BSU35340; -.
DR   PaxDb; P39738; -.
DR   PRIDE; P39738; -.
DR   EnsemblBacteria; CAB15551; CAB15551; BSU_35340.
DR   GeneID; 936728; -.
DR   KEGG; bsu:BSU35340; -.
DR   PATRIC; fig|224308.179.peg.3825; -.
DR   eggNOG; COG1345; Bacteria.
DR   InParanoid; P39738; -.
DR   OMA; TLEWQRD; -.
DR   PhylomeDB; P39738; -.
DR   BioCyc; BSUB:BSU35340-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0009421; C:bacterial-type flagellum filament cap; IBA:GO_Central.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IBA:GO_Central.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR040026; FliD.
DR   InterPro; IPR010809; FliD_C.
DR   InterPro; IPR003481; FliD_N.
DR   PANTHER; PTHR30288; PTHR30288; 1.
DR   Pfam; PF07196; Flagellin_IN; 1.
DR   Pfam; PF07195; FliD_C; 1.
DR   Pfam; PF02465; FliD_N; 1.
PE   1: Evidence at protein level;
KW   Bacterial flagellum; Coiled coil; Reference proteome; Secreted.
FT   CHAIN           1..498
FT                   /note="Flagellar hook-associated protein 2"
FT                   /id="PRO_0000177014"
FT   COILED          448..471
FT                   /evidence="ECO:0000255"
FT   CONFLICT        9
FT                   /note="A -> E (in Ref. 1; CAA83248)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   498 AA;  54505 MW;  08254112E9564E5F CRC64;
     MVTRITGLAS GMDIDDIVSK LMQTERAPLD KLTQKKQTLE WQRDSYREVN SKIKELQDYM
     SKNTLTYPST YQSKTVTSSN ESVLTATGSV SAPNSSSTVE VASLATAATY KANNYTGYTQ
     GDYNLAFNVV APGETTAKTV NISVTSADTI DNVISKLNSS DLGVSAFKDK IWNGTEYVET
     IAFSSKATGA GGSIQAADSA TADFMSGQLG FSLDADNKLT AYKEGTNAKV TINGFEMEKL
     TNNFTVNGVT YSIKNTTAAT GPVTTSVSTD VDGIYNQIKE FVDKYNELVD SLNEKLKEEK
     YRDYTPLTSE QKEAMSDKEV ELWEEKAKSG LLRNDSSIST GTNQMRTDFY TQVNADGKTY
     QLTEFGITTS SAYQLRGHLE INEEKLKAKI AEDPQGVANL FTSGTNDSNY SDKGIMKRIT
     NTLRSTVKSI EAKAGNSTMG ASSYSIGKNL NSISTEITDM QDRLNTIENR YYSKFSAMDS
     AIQKMNEQAS YLSQLLVQ