ID   FLID_BORBU              Reviewed;         665 AA.
AC   O51173; P94264;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Flagellar hook-associated protein 2;
DE            Short=HAP2;
DE   AltName: Full=Filament cap protein;
DE   AltName: Full=Flagellar cap protein;
GN   Name=fliD; OrderedLocusNames=BB_0149;
OS   Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS   (Borrelia burgdorferi).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=224326;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA   Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA   Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA   van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA   Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA   Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA   Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL   Nature 390:580-586(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 110-665.
RC   STRAIN=212;
RX   PubMed=9168617; DOI=10.1099/00221287-143-5-1681;
RA   Ge Y., Old I.G., Saint-Girons I., Charon N.W.;
RT   "The flgK motility operon of Borrelia burgdorferi is initiated by a sigma
RT   70-like promoter.";
RL   Microbiology 143:1681-1690(1997).
CC   -!- FUNCTION: Required for the morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homopentamer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Periplasmic flagellum. Periplasm.
CC   -!- SIMILARITY: Belongs to the FliD family. {ECO:0000305}.
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DR   EMBL; AE000783; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U66699; AAB58986.1; -; Genomic_DNA.
DR   PIR; E70118; E70118.
DR   RefSeq; WP_002659773.1; NC_001318.1.
DR   RefSeq; YP_008686561.1; NC_001318.1.
DR   AlphaFoldDB; O51173; -.
DR   SMR; O51173; -.
DR   PRIDE; O51173; -.
DR   PATRIC; fig|224326.49.peg.547; -.
DR   OMA; FIGAYNE; -.
DR   Proteomes; UP000001807; Chromosome.
DR   GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:InterPro.
DR   GO; GO:0055040; C:periplasmic flagellum; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR040026; FliD.
DR   InterPro; IPR010809; FliD_C.
DR   InterPro; IPR003481; FliD_N.
DR   PANTHER; PTHR30288; PTHR30288; 1.
DR   Pfam; PF07195; FliD_C; 1.
DR   Pfam; PF02465; FliD_N; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Coiled coil; Periplasm; Reference proteome.
FT   CHAIN           1..665
FT                   /note="Flagellar hook-associated protein 2"
FT                   /id="PRO_0000177015"
FT   COILED          602..658
FT                   /evidence="ECO:0000255"
FT   VARIANT         126
FT                   /note="G -> R (in strain: 212)"
FT   VARIANT         227
FT                   /note="N -> D (in strain: 212)"
FT   VARIANT         264
FT                   /note="V -> I (in strain: 212)"
FT   VARIANT         284
FT                   /note="Missing (in strain: 212)"
FT   VARIANT         289
FT                   /note="D -> A (in strain: 212)"
FT   VARIANT         304
FT                   /note="D -> S (in strain: 212)"
FT   VARIANT         310
FT                   /note="E -> P (in strain: 212)"
FT   VARIANT         370..371
FT                   /note="NV -> KL (in strain: 212)"
FT   VARIANT         424
FT                   /note="P -> A (in strain: 212)"
FT   VARIANT         480
FT                   /note="T -> A (in strain: 212)"
FT   CONFLICT        110..126
FT                   /note="VFLSSNFDPKKVTIPEG -> CFCLQILILKKLQSQR (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   665 AA;  74718 MW;  8BE25E27EAE0A383 CRC64;
     MASGFFVPGL ESKYNTKEIR ESMLKSDKAK IDSSFKKLES LEQEKSAWQL INRKISTLNS
     LAKELTSLNS PFNLMSGNSS NSEVLTLSTR YGSKNETHKL IVDQIASADV FLSSNFDPKK
     VTIPEGDYIF LVGKKEINVK SNGNIDLLVK DINNKGKGFL SAKIVKSDKN GNSRFVLQSL
     KEGKENKLVI KGEGLSFAKQ IGILSELKTN FNPNLSDIVV NQSSSNNKLA FENNGLVLNP
     LSEVSIEIPE DIEITSRSKI KFEVKYFDTG LEEPDSKIIF NPGGATFKDA KVESEDSVVD
     LGSDLKTPLE KKYIQMNMVK ICSKEGSLEL PLINISNNFE EVEVDVGALS NLEEINIENK
     ANNKVIVISN VEIFDPKNRD GHLPINAKSF AENAKIKFDG VDVERDSNVI NDLVPNVTLS
     LKKPSSDMVE AKIEPDYEGI KRVLLDFIGA YNEVLAEINI VSSNEDQPNN QKSNIVEELT
     YLSDSQKEEA YKNLGILRSE FLLKNLKSKL ESIIFKPYVT SDPNFSIINQ MGVFTNSISS
     SGGLSRYLRL DEKKFDESIR NNIDNVRELF LYDLNGDRVY DNGIAKMLGD CLSPLVASGG
     VIYNKIKNYD LKIFNQKNKV EDYKKKYEDR ERKVEGELNT LDFTVKRMKD QENTLKAFDF
     NQRNK