ID   FLID_THEMA              Reviewed;         608 AA.
AC   Q9X0K7;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Flagellar hook-associated protein 2;
DE            Short=HAP2;
DE   AltName: Full=Filament cap protein;
DE   AltName: Full=Flagellar cap protein;
GN   Name=fliD; OrderedLocusNames=TM_1123;
OS   Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS   / MSB8).
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=243274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX   PubMed=10360571; DOI=10.1038/20601;
RA   Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA   Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA   Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA   Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA   Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA   Smith H.O., Venter J.C., Fraser C.M.;
RT   "Evidence for lateral gene transfer between Archaea and Bacteria from
RT   genome sequence of Thermotoga maritima.";
RL   Nature 399:323-329(1999).
CC   -!- FUNCTION: Required for the morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homopentamer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- SIMILARITY: Belongs to the FliD family. {ECO:0000305}.
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DR   EMBL; AE000512; AAD36199.1; -; Genomic_DNA.
DR   PIR; H72292; H72292.
DR   RefSeq; NP_228929.1; NC_000853.1.
DR   RefSeq; WP_004080294.1; NZ_CP011107.1.
DR   AlphaFoldDB; Q9X0K7; -.
DR   STRING; 243274.THEMA_08730; -.
DR   DNASU; 898641; -.
DR   EnsemblBacteria; AAD36199; AAD36199; TM_1123.
DR   KEGG; tma:TM1123; -.
DR   eggNOG; COG1345; Bacteria.
DR   InParanoid; Q9X0K7; -.
DR   OMA; YLWELGI; -.
DR   OrthoDB; 883503at2; -.
DR   Proteomes; UP000008183; Chromosome.
DR   GO; GO:0009421; C:bacterial-type flagellum filament cap; IBA:GO_Central.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IBA:GO_Central.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR040026; FliD.
DR   InterPro; IPR010809; FliD_C.
DR   InterPro; IPR003481; FliD_N.
DR   PANTHER; PTHR30288; PTHR30288; 2.
DR   Pfam; PF07196; Flagellin_IN; 2.
DR   Pfam; PF07195; FliD_C; 1.
DR   Pfam; PF02465; FliD_N; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Coiled coil; Reference proteome; Secreted.
FT   CHAIN           1..608
FT                   /note="Flagellar hook-associated protein 2"
FT                   /id="PRO_0000177025"
FT   COILED          47..75
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   608 AA;  67511 MW;  D680BF088C13A87D CRC64;
     MDLSKIASTI NMRYYSQLGG FQVGGAVSGL DTQSIINAIL EAESQPLQNL TEKYEKYELM
     QEAYTEVKTK LREFRDLVYS FKLQSTVVQK TAVSSSSLLS AEASSVAVTG VYHVKIVQTA
     TYTTLAGASE VVPPPDSTKT FGELDYMYTP QEGTVRLYNN ETGNYVEVQV LSTDTIDDIV
     SKLNSALSSA GITGSVSYDT STGKISITSD KNFSLVDITG NFTKVFHLDE ASLNYSGGNY
     SFTSTASVSG LSTAKTLQQI ATYTSKTIIS GKVKINGVEI DVDQNDTLSS LIEKINDSEA
     GVTASYDYHA NRVVIISKTS GPEAITLEDT YGTGLFSLLG IENHSLYVGQ KAHLQISMDG
     TNWADVYSDT NDVEYNGVTF HISGMTSETI TVDVRVDTDA IVEKIKEFVD KWNETMDYLN
     EKLTEESITD KDEEEMTEEE KMKGVLKGDD LLEEIFSRLR GFITYKAEGD INYLWELGIS
     TGDIGTGYEN MMKGHLEVDE EKLKQIVEED PNKVWEFFGG ENGFATQLDD YLWELVKFNG
     RIDQVAGISG RIEREQRFLA TQIASWIERL SKREQELWRK FSVMEEVISQ LQSQGSWISQ
     ALQGSSNK