ID   AKTP2_DROPS             Reviewed;         262 AA.
AC   Q28YD9;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 2.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Protein crossbronx-like;
GN   ORFNames=GA14202;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- SIMILARITY: Belongs to the ubiquitin-conjugating enzyme family. FTS
CC       subfamily. {ECO:0000255|PROSITE-ProRule:PRU00388}.
CC   -!- CAUTION: Lacks the conserved Cys residue necessary for ubiquitin-
CC       conjugating enzyme E2 activity. {ECO:0000305}.
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DR   EMBL; CM000071; EAL26026.2; -; Genomic_DNA.
DR   RefSeq; XP_001361448.2; XM_001361411.3.
DR   AlphaFoldDB; Q28YD9; -.
DR   SMR; Q28YD9; -.
DR   STRING; 7237.FBpp0276200; -.
DR   EnsemblMetazoa; FBtr0277762; FBpp0276200; FBgn0074231.
DR   GeneID; 4804973; -.
DR   KEGG; dpo:Dpse_GA14202; -.
DR   eggNOG; KOG0429; Eukaryota.
DR   HOGENOM; CLU_083049_2_0_1; -.
DR   InParanoid; Q28YD9; -.
DR   OMA; DQHHIWH; -.
DR   Proteomes; UP000001819; Chromosome 3.
DR   Bgee; FBgn0074231; Expressed in male reproductive system and 1 other tissue.
DR   Gene3D; 3.10.110.10; -; 1.
DR   InterPro; IPR000608; UBQ-conjugat_E2.
DR   InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR   Pfam; PF00179; UQ_con; 1.
DR   SUPFAM; SSF54495; SSF54495; 1.
DR   PROSITE; PS50127; UBC_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..262
FT                   /note="Protein crossbronx-like"
FT                   /id="PRO_0000379047"
FT   DOMAIN          15..179
FT                   /note="UBC core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00388"
SQ   SEQUENCE   262 AA;  29968 MW;  A9CC79146CFE60D2 CRC64;
     MWFSWNNTEQ SIAVRQGYQV LAEYQLIEQE QLKNIYAIPS YASALHWFGV IFIHSGFYAG
     SMFRFSIILP DNFPNGTSLP TIIFTTTCYH PHIRPQTQSL DLAPFFTGWR KDHYHVWHLL
     KYIQAIFADP EGSISTTVTP SGDRVCLEEA YNMDALAMLS NDRVAFIKKV QELALFTKKH
     MYDKPTSNDP HYIVIEPFCS ERHTKIMEQL KSPSWKEATS MDTSPPAQCL ARIDSSRQMD
     EEEAKQSAKL FAKNGKAAAA LQ