ID   FLID_VIBCH              Reviewed;         666 AA.
AC   Q9KQ63;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Flagellar hook-associated protein 2;
DE            Short=HAP2;
DE   AltName: Full=Filament cap protein;
DE   AltName: Full=Flagellar cap protein;
GN   Name=fliD; OrderedLocusNames=VC_2140;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Required for the morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homopentamer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted. Bacterial flagellum.
CC   -!- SIMILARITY: Belongs to the FliD family. {ECO:0000305}.
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DR   EMBL; AE003852; AAF95285.1; -; Genomic_DNA.
DR   PIR; G82111; G82111.
DR   RefSeq; NP_231771.1; NC_002505.1.
DR   RefSeq; WP_000052031.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KQ63; -.
DR   SMR; Q9KQ63; -.
DR   STRING; 243277.VC_2140; -.
DR   PRIDE; Q9KQ63; -.
DR   DNASU; 2613276; -.
DR   EnsemblBacteria; AAF95285; AAF95285; VC_2140.
DR   GeneID; 57740759; -.
DR   KEGG; vch:VC_2140; -.
DR   PATRIC; fig|243277.26.peg.2045; -.
DR   eggNOG; COG1345; Bacteria.
DR   HOGENOM; CLU_015182_2_0_6; -.
DR   OMA; TLEWQRD; -.
DR   BioCyc; VCHO:VC2140-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0009421; C:bacterial-type flagellum filament cap; IBA:GO_Central.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IBA:GO_Central.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR040026; FliD.
DR   InterPro; IPR010809; FliD_C.
DR   InterPro; IPR003481; FliD_N.
DR   PANTHER; PTHR30288; PTHR30288; 1.
DR   Pfam; PF07196; Flagellin_IN; 1.
DR   Pfam; PF07195; FliD_C; 1.
DR   Pfam; PF02465; FliD_N; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Coiled coil; Reference proteome; Secreted.
FT   CHAIN           1..666
FT                   /note="Flagellar hook-associated protein 2"
FT                   /id="PRO_0000177028"
FT   COILED          354..419
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   666 AA;  72331 MW;  6794EFEC34A2A0D2 CRC64;
     MSLGPMGMNT GFDINGMVSK IVSAERVPKQ QRIDNERTNI DTSISAYGRL RESLDTMKNL
     MTQFRQEKAF AVRKVDTSNE QVVSATATTE AIAGNYSVDV LQLAQSHKIA SEVLDKDAKF
     GPGKLHISLG DKSFTLDVQG NSKLVDIVRG INGEKSNPGV RASIINDVEG PRLIVASNVS
     GKDHSVKMSA QAEPGNPLKQ LEYKTLEQRV RDLEKARAQA QQLIAPLTPE QQKVAAKVAE
     KIGDAARLVD QEVAQEIRSA AQSAQGAAGE ALNAGELTES AVKAAANAAS EAKKYIRPED
     RIPGWTETAS GTLLDSYWEP EEELDAQGQK KAADVPGWSN TASGTLLDSY VTPQEAQQKL
     EQKLAQEKAQ IEAAIRSGKM TPEEAKAQAR AKLSPEERAY IEQVEKAQAA LNAAQSAFDG
     YGGMTEVQSA QDSMVVLDGV ATLSSNNNII ENAIEGVNLT LKGKTDRNQP PAEIGIEYDR
     ERVRNDIEQF VAAYNQFFQT SKELAGVDPR TGQAGPLAGD SIVRSADSRL KTVFSSSIEQ
     APENLKSLTE FGITTTRQGT LEINYAMLDR QLNNNFTKLG EFFGGNQGFA KRVEDAISSM
     TGVTGSIRTR EKSLNEQTYR LDDDQRSLDR RMESLEKRTH AKFSAMQDAT SKMQSQLAGM
     MNALGG