FLIF_PSEAE
ID FLIF_PSEAE Reviewed; 598 AA.
AC Q51463;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 08-DEC-2000, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Flagellar M-ring protein;
GN Name=fliF; OrderedLocusNames=PA1101;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PAK;
RX PubMed=8675317; DOI=10.1128/iai.64.6.2130-2136.1996;
RA Arora S.K., Ritchings B.W., Almira E.C., Lory S., Ramphal R.;
RT "Cloning and characterization of Pseudomonas aeruginosa fliF, necessary for
RT flagellar assembly and bacterial adherence to mucin.";
RL Infect. Immun. 64:2130-2136(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: The M ring may be actively involved in energy transduction.
CC {ECO:0000250}.
CC -!- SUBUNIT: The basal body constitutes a major portion of the flagellar
CC organelle and consists of four rings (L,P,S, and M) mounted on a
CC central rod. The M ring is integral to the inner membrane of the cell
CC and may be connected to the flagellar rod via the S ring. The S
CC (supramembrane ring) lies just distal to the M ring. The L and P rings
CC lie in the outer membrane and the periplasmic space, respectively (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}. Bacterial flagellum basal body
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FliF family. {ECO:0000305}.
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DR EMBL; L43507; AAB06801.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG04490.1; -; Genomic_DNA.
DR PIR; F83508; F83508.
DR RefSeq; NP_249792.1; NC_002516.2.
DR RefSeq; WP_003109118.1; NZ_QZGE01000006.1.
DR AlphaFoldDB; Q51463; -.
DR SMR; Q51463; -.
DR STRING; 287.DR97_836; -.
DR PaxDb; Q51463; -.
DR PRIDE; Q51463; -.
DR EnsemblBacteria; AAG04490; AAG04490; PA1101.
DR GeneID; 881927; -.
DR KEGG; pae:PA1101; -.
DR PATRIC; fig|208964.12.peg.1140; -.
DR PseudoCAP; PA1101; -.
DR HOGENOM; CLU_028108_1_1_6; -.
DR InParanoid; Q51463; -.
DR OMA; NYEVNRI; -.
DR PhylomeDB; Q51463; -.
DR BioCyc; PAER208964:G1FZ6-1124-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0009431; C:bacterial-type flagellum basal body, MS ring; IEA:InterPro.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR013556; Flag_M-ring_C.
DR InterPro; IPR000067; FlgMring_FliF.
DR InterPro; IPR006182; FliF_N_dom.
DR InterPro; IPR043427; YscJ/FliF.
DR PANTHER; PTHR30046; PTHR30046; 1.
DR PANTHER; PTHR30046:SF0; PTHR30046:SF0; 1.
DR Pfam; PF01514; YscJ_FliF; 1.
DR Pfam; PF08345; YscJ_FliF_C; 1.
DR PIRSF; PIRSF004862; FliF; 1.
DR PRINTS; PR01009; FLGMRINGFLIF.
DR TIGRFAMs; TIGR00206; fliF; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..598
FT /note="Flagellar M-ring protein"
FT /id="PRO_0000180884"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 488..508
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 296..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 251
FT /note="G -> D (in Ref. 1; AAB06801)"
FT /evidence="ECO:0000305"
FT CONFLICT 277
FT /note="G -> D (in Ref. 1; AAB06801)"
FT /evidence="ECO:0000305"
FT CONFLICT 281..283
FT /note="YKA -> NKT (in Ref. 1; AAB06801)"
FT /evidence="ECO:0000305"
FT CONFLICT 313
FT /note="R -> H (in Ref. 1; AAB06801)"
FT /evidence="ECO:0000305"
FT CONFLICT 505
FT /note="V -> M (in Ref. 1; AAB06801)"
FT /evidence="ECO:0000305"
FT CONFLICT 530
FT /note="G -> GG (in Ref. 1; AAB06801)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 598 AA; 64050 MW; 4F990661F1B25BF4 CRC64;
MADALIDSQV PAKSGGAGML KKSFPGLSFL DNLSEMTMLR QIGLLVGLAA SVAIGFAVVL
WSQQPDYKPL YGSLNGVDAN RVVEALTAAD IPYKVEPNSG ALLVKADDLG RARMKVASAG
VAPTDNNVGF EILDKEQALG TSQFMEATNY RRGLEGELAR TVSSLNNVKA ARVHLAIPKS
SVFVRDDRKP SASVLVELYP GRSLEPSQVM AIVNLVATSV PELDKSQVTV VDQKGNLLSD
QQELSELTMA GKQFDFTRRM EGLLTQRVHN ILQPVLGNGR YKAEVSADVD FSAVESTSEM
YNPDQPALRS EQRNNEERQN SSGPQGVPGA LSNQPPGPAS APQQATASAP ADYVAPGQPL
KDANGQTIID PKTGKPELAP YPTDKRDQTT RNYELDRSIS YTKQQQGRLR RLSVAVVLDD
QMKVDAKTGE VSHQPWSADE LARFTRLVQD SVGYDASRGD SVSVINAPFA PAQAEEIDSI
PFYSQPWFWD IVKQVLGVLF ILVLVFGVLR PVLSNITGGG KGKSLAGGGG RDGDLALGES
GLEGSLADDR VSIGGPSSIL LPSPTEGYDA QLNAIKNLVA QDPGRVAQVV KEWINADE
