位置:首页 > 蛋白库 > FLIF_SALTY
FLIF_SALTY
ID   FLIF_SALTY              Reviewed;         560 AA.
AC   P15928;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=Flagellar M-ring protein;
GN   Name=fliF; Synonyms=fla AII.1, fla BI; OrderedLocusNames=STM1969;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2544561; DOI=10.1128/jb.171.7.3890-3900.1989;
RA   Jones C.J., Homma M., Macnab R.M.;
RT   "L-, P-, and M-ring proteins of the flagellar basal body of Salmonella
RT   typhimurium: gene sequences and deduced protein sequences.";
RL   J. Bacteriol. 171:3890-3900(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-27.
RC   STRAIN=SJW1103;
RX   PubMed=1551848; DOI=10.1128/jb.174.7.2298-2304.1992;
RA   Mueller V., Jones C.J., Kawagishi I., Aizawa S., Macnab R.M.;
RT   "Characterization of the fliE genes of Escherichia coli and Salmonella
RT   typhimurium and identification of the FliE protein as a component of the
RT   flagellar hook-basal body complex.";
RL   J. Bacteriol. 174:2298-2304(1992).
RN   [4]
RP   INDUCTION.
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=21278297; DOI=10.1128/jb.01494-10;
RA   Wada T., Morizane T., Abo T., Tominaga A., Inoue-Tanaka K., Kutsukake K.;
RT   "EAL domain protein YdiV acts as an anti-FlhD4C2 factor responsible for
RT   nutritional control of the flagellar regulon in Salmonella enterica Serovar
RT   Typhimurium.";
RL   J. Bacteriol. 193:1600-1611(2011).
CC   -!- FUNCTION: The M ring may be actively involved in energy transduction.
CC   -!- SUBUNIT: The basal body constitutes a major portion of the flagellar
CC       organelle and consists of four rings (L,P,S, and M) mounted on a
CC       central rod. The M ring is integral to the inner membrane of the cell
CC       and may be connected to the flagellar rod via the S ring. The S
CC       (supramembrane ring) lies just distal to the M ring. The L and P rings
CC       lie in the outer membrane and the periplasmic space, respectively.
CC   -!- INTERACTION:
CC       P15928; P0A1J9: fliG; NbExp=4; IntAct=EBI-2012119, EBI-2012130;
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC       Bacterial flagellum basal body.
CC   -!- INDUCTION: Inhibited in nutrient-poor medium.
CC       {ECO:0000269|PubMed:21278297}.
CC   -!- SIMILARITY: Belongs to the FliF family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M24462; AAA27096.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20881.1; -; Genomic_DNA.
DR   EMBL; M84993; AAA27094.1; -; Genomic_DNA.
DR   PIR; C32887; D30930.
DR   RefSeq; NP_460922.1; NC_003197.2.
DR   RefSeq; WP_001276834.1; NC_003197.2.
DR   PDB; 6SCN; EM; 3.10 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d=1-560.
DR   PDB; 6SD1; EM; 2.60 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d=1-560.
DR   PDB; 6SD2; EM; 3.10 A; A/C/D/F/G/I/J/L/N/O/Q/R/T/U/W/Y/Z/b/c/e/f=1-560.
DR   PDB; 6SD3; EM; 3.30 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d=1-560.
DR   PDB; 6SD4; EM; 2.80 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d=1-560.
DR   PDB; 6SD5; EM; 3.10 A; A/C/D/F/G/I/J/L/M/O/P/R/T/U/W/X/Z/a/c/d/f/g=1-560.
DR   PDB; 6TRE; EM; 3.30 A; 1/2/3/4/5/6/A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X=1-560.
DR   PDB; 7BK0; EM; 3.80 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d=1-560.
DR   PDB; 7CG0; EM; 3.20 A; 5/6/7/8/9=311-331.
DR   PDB; 7CG7; EM; 3.61 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d=1-560.
DR   PDB; 7D84; EM; 3.70 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d=1-560.
DR   PDB; 7E80; EM; 3.67 A; 5/6/7/8/9=311-331.
DR   PDB; 7E81; EM; 4.50 A; Ca/Cb/Cc/Cd/Ce/Cf/Ch/Ci/Cj/Ck/Cl/Cm/Cn/Co/Cp/Cq/Cr/Cs/Ct/Cu/Cv/Cw/Cx/Cy/Cz/Da/Db/Dc/Dd/De=1-560.
DR   PDB; 7E82; EM; 3.30 A; 5/6/7/8/9=311-331.
DR   PDB; 7NVG; EM; 3.70 A; A1/B1/C1/D1/E1/F1/G1/H1/I1/J1/K1/L1/M1/N1/O1/P1/Q1/R1/S1/T1/U1/V1/W1/X1/Y1/Z1/a1/b1/c1/d1=1-560.
DR   PDBsum; 6SCN; -.
DR   PDBsum; 6SD1; -.
DR   PDBsum; 6SD2; -.
DR   PDBsum; 6SD3; -.
DR   PDBsum; 6SD4; -.
DR   PDBsum; 6SD5; -.
DR   PDBsum; 6TRE; -.
DR   PDBsum; 7BK0; -.
DR   PDBsum; 7CG0; -.
DR   PDBsum; 7CG7; -.
DR   PDBsum; 7D84; -.
DR   PDBsum; 7E80; -.
DR   PDBsum; 7E81; -.
DR   PDBsum; 7E82; -.
DR   PDBsum; 7NVG; -.
DR   AlphaFoldDB; P15928; -.
DR   SMR; P15928; -.
DR   IntAct; P15928; 2.
DR   STRING; 99287.STM1969; -.
DR   TCDB; 3.A.6.2.1; the type iii (virulence-related) secretory pathway (iiisp) family.
DR   PaxDb; P15928; -.
DR   PRIDE; P15928; -.
DR   EnsemblBacteria; AAL20881; AAL20881; STM1969.
DR   GeneID; 1253490; -.
DR   KEGG; stm:STM1969; -.
DR   PATRIC; fig|99287.12.peg.2086; -.
DR   HOGENOM; CLU_028108_1_0_6; -.
DR   OMA; NYEVNRI; -.
DR   PhylomeDB; P15928; -.
DR   BioCyc; SENT99287:STM1969-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009431; C:bacterial-type flagellum basal body, MS ring; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR   Gene3D; 3.30.300.30; -; 1.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR013556; Flag_M-ring_C.
DR   InterPro; IPR000067; FlgMring_FliF.
DR   InterPro; IPR006182; FliF_N_dom.
DR   InterPro; IPR043427; YscJ/FliF.
DR   PANTHER; PTHR30046; PTHR30046; 1.
DR   PANTHER; PTHR30046:SF0; PTHR30046:SF0; 1.
DR   Pfam; PF01514; YscJ_FliF; 1.
DR   Pfam; PF08345; YscJ_FliF_C; 1.
DR   PIRSF; PIRSF004862; FliF; 1.
DR   PRINTS; PR01009; FLGMRINGFLIF.
DR   TIGRFAMs; TIGR00206; fliF; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Bacterial flagellum; Cell inner membrane; Cell membrane;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   INIT_MET        1
FT                   /note="Removed"
FT   CHAIN           2..560
FT                   /note="Flagellar M-ring protein"
FT                   /id="PRO_0000180883"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        455..475
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          304..372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        330..365
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   HELIX           126..145
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   STRAND          146..152
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   STRAND          156..158
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   STRAND          173..177
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   HELIX           188..199
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   STRAND          200..202
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   HELIX           207..209
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   STRAND          210..213
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   STRAND          215..217
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   TURN            222..225
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   STRAND          227..230
FT                   /evidence="ECO:0007829|PDB:6SCN"
FT   HELIX           232..252
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   HELIX           254..257
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   STRAND          259..271
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   STRAND          274..278
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   TURN            288..290
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   STRAND          292..302
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   STRAND          316..319
FT                   /evidence="ECO:0007829|PDB:7CG0"
FT   STRAND          358..367
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   STRAND          370..376
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   STRAND          381..391
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   HELIX           406..420
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   TURN            424..427
FT                   /evidence="ECO:0007829|PDB:6SD1"
FT   STRAND          429..434
FT                   /evidence="ECO:0007829|PDB:6SD1"
SQ   SEQUENCE   560 AA;  61230 MW;  7A5011F4EF17B488 CRC64;
     MSATASTATQ PKPLEWLNRL RANPRIPLIV AGSAAVAIVV AMVLWAKTPD YRTLFSNLSD
     QDGGAIVAQL TQMNIPYRFA NGSGAIEVPA DKVHELRLRL AQQGLPKGGA VGFELLDQEK
     FGISQFSEQV NYQRALEGEL ARTIETLGPV KSARVHLAMP KPSLFVREQK SPSASVTVTL
     EPGRALDEGQ ISAVVHLVSS AVAGLPPGNV TLVDQSGHLL TQSNTSGRDL NDAQLKFAND
     VESRIQRRIE AILSPIVGNG NVHAQVTAQL DFANKEQTEE HYSPNGDASK ATLRSRQLNI
     SEQVGAGYPG GVPGALSNQP APPNEAPIAT PPTNQQNAQN TPQTSTSTNS NSAGPRSTQR
     NETSNYEVDR TIRHTKMNVG DIERLSVAVV VNYKTLADGK PLPLTADQMK QIEDLTREAM
     GFSDKRGDTL NVVNSPFSAV DNTGGELPFW QQQSFIDQLL AAGRWLLVLV VAWILWRKAV
     RPQLTRRVEE AKAAQEQAQV RQETEEAVEV RLSKDEQLQQ RRANQRLGAE VMSQRIREMS
     DNDPRVVALV IRQWMSNDHE
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024