ID   FLIG_BACSU              Reviewed;         338 AA.
AC   P23448;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=Flagellar motor switch protein FliG;
GN   Name=fliG; OrderedLocusNames=BSU16220;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=1828465; DOI=10.1128/jb.173.11.3573-3579.1991;
RA   Albertini A.M., Caramori T., Crabb W.D., Scoffone F., Galizzi A.;
RT   "The flaA locus of Bacillus subtilis is part of a large operon coding for
RT   flagellar structures, motility functions, and an ATPase-like polypeptide.";
RL   J. Bacteriol. 173:3573-3579(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: One of the proteins that forms a switch complex that is
CC       proposed to be located at the base of the basal body. This complex
CC       interacts with chemotaxis proteins (such as CheY) in addition to
CC       contacting components of the motor that determine the direction of
CC       flagellar rotation.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Bacterial
CC       flagellum basal body {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FliG family. {ECO:0000305}.
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DR   EMBL; X56049; CAA39521.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB13495.1; -; Genomic_DNA.
DR   PIR; B42365; B42365.
DR   RefSeq; NP_389504.1; NC_000964.3.
DR   RefSeq; WP_003231981.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; P23448; -.
DR   SMR; P23448; -.
DR   STRING; 224308.BSU16220; -.
DR   jPOST; P23448; -.
DR   PaxDb; P23448; -.
DR   PRIDE; P23448; -.
DR   EnsemblBacteria; CAB13495; CAB13495; BSU_16220.
DR   GeneID; 50133523; -.
DR   GeneID; 937577; -.
DR   KEGG; bsu:BSU16220; -.
DR   PATRIC; fig|224308.179.peg.1762; -.
DR   eggNOG; COG1536; Bacteria.
DR   InParanoid; P23448; -.
DR   OMA; QVRPFEF; -.
DR   PhylomeDB; P23448; -.
DR   BioCyc; BSUB:BSU16220-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IMP:CACAO.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IBA:GO_Central.
DR   GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IMP:CACAO.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   InterPro; IPR000090; Flg_Motor_Flig.
DR   InterPro; IPR023087; Flg_Motor_Flig_C.
DR   InterPro; IPR011002; FliG_a-hlx.
DR   InterPro; IPR032779; FliG_M.
DR   InterPro; IPR028263; FliG_N.
DR   PANTHER; PTHR30534; PTHR30534; 1.
DR   Pfam; PF01706; FliG_C; 1.
DR   Pfam; PF14841; FliG_M; 1.
DR   Pfam; PF14842; FliG_N; 1.
DR   PIRSF; PIRSF003161; FliG; 1.
DR   PRINTS; PR00954; FLGMOTORFLIG.
DR   SUPFAM; SSF48029; SSF48029; 2.
DR   TIGRFAMs; TIGR00207; fliG; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Cell membrane; Chemotaxis; Flagellar rotation;
KW   Membrane; Reference proteome.
FT   CHAIN           1..338
FT                   /note="Flagellar motor switch protein FliG"
FT                   /id="PRO_0000184082"
FT   MOTIF           129..132
FT                   /note="Part of the EHPQR-motif"
FT   SITE            164
FT                   /note="Part of the EHPQR-motif"
SQ   SEQUENCE   338 AA;  38191 MW;  8C44193BA0ADE58E CRC64;
     MARRDQDKLT GKQKAAILMI SLGLDVSASV YKHLTDEEIE RLTLEISGVR SVDHQKKDEI
     IEEFHNIAIA QDYISQGGLS YARQVLEKAL GEDKAENILN RLTSSLQVKP FDFARKAEPE
     QILNFIQQEH PQTMALILSY LDPVQAGQIL SELNPEVQAE VARRIAVMDR TSPEIINEVE
     RILEQKLSSA FTQDYTQTGG IEAVVEVLNG VDRGTEKTIL DSLEIQDPDL AEEIKKRMFV
     FEDIVTLDNR AIQRVIRDVE NDDLLLSLKV ASEEVKEIVF NNMSQRMVET FKEEMEFMGP
     VRLKDVEEAQ SRIVSIVRKL EEAGEIVIAR GGGDDIIV