FLIG_CAUVC
ID FLIG_CAUVC Reviewed; 340 AA.
AC Q04955;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Flagellar motor switch protein FliG;
GN Name=fliG; OrderedLocusNames=CC_0906;
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=8002583; DOI=10.1128/jb.176.24.7587-7600.1994;
RA Ramakrishnan G., Zhao J.L., Newton A.;
RT "Multiple structural proteins are required for both transcriptional
RT activation and negative autoregulation of Caulobacter crescentus flagellar
RT genes.";
RL J. Bacteriol. 176:7587-7600(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- FUNCTION: FliG is one of three proteins (FliG, FliN, FliM) that forms
CC the rotor-mounted switch complex (C ring), located at the base of the
CC basal body. This complex interacts with the CheY and CheZ chemotaxis
CC proteins, in addition to contacting components of the motor that
CC determine the direction of flagellar rotation (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Peripheral
CC membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
CC Bacterial flagellum basal body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FliG family. {ECO:0000305}.
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DR EMBL; M98855; AAA66326.1; -; Genomic_DNA.
DR EMBL; AE005673; AAK22890.1; -; Genomic_DNA.
DR PIR; B55544; B55544.
DR RefSeq; NP_419722.1; NC_002696.2.
DR RefSeq; WP_010918790.1; NC_002696.2.
DR AlphaFoldDB; Q04955; -.
DR SMR; Q04955; -.
DR STRING; 190650.CC_0906; -.
DR PRIDE; Q04955; -.
DR EnsemblBacteria; AAK22890; AAK22890; CC_0906.
DR KEGG; ccr:CC_0906; -.
DR PATRIC; fig|190650.5.peg.919; -.
DR eggNOG; COG1536; Bacteria.
DR HOGENOM; CLU_047835_0_0_5; -.
DR OMA; QVRPFEF; -.
DR BioCyc; CAULO:CC0906-MON; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR InterPro; IPR000090; Flg_Motor_Flig.
DR InterPro; IPR023087; Flg_Motor_Flig_C.
DR InterPro; IPR011002; FliG_a-hlx.
DR InterPro; IPR032779; FliG_M.
DR InterPro; IPR028263; FliG_N.
DR PANTHER; PTHR30534; PTHR30534; 1.
DR Pfam; PF01706; FliG_C; 1.
DR Pfam; PF14841; FliG_M; 1.
DR Pfam; PF14842; FliG_N; 1.
DR PIRSF; PIRSF003161; FliG; 1.
DR PRINTS; PR00954; FLGMOTORFLIG.
DR SUPFAM; SSF48029; SSF48029; 2.
DR TIGRFAMs; TIGR00207; fliG; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum; Cell inner membrane; Cell membrane; Chemotaxis;
KW Flagellar rotation; Membrane; Reference proteome.
FT CHAIN 1..340
FT /note="Flagellar motor switch protein FliG"
FT /id="PRO_0000184088"
SQ SEQUENCE 340 AA; 37684 MW; B3442EC207901ED5 CRC64;
MAMKLAVNDV KNLSGPEKAA IVLLALGEDH TRIWEALDDE EIKEVSQAMA GLGTVSASVV
EDLLVEFVSG MSSTGAIMGS YEQTQRLLAS FMPQDKVDAL MEEIRGPAGR TMWDKLGNVN
EAVLANYLKN EYPQTVAVVL SKVKSDHAAR VLACLPEDFA LECVTRMLRM EPVQREILDK
IEMTLRTEFM SNLARTSKRD SHEMMAEIFN NFDRQTEARF IAALEERNRE AAERIRALMF
VFEDLSKLDP GGIQTLLRGT PKEQLALALK GASDKLRDLF FSNMSERAAK IMREDMDSMG
PVRLKDVDAA QVGMVQVAKD LAAKGEIMLA GSGADDELIY