FLIG_RHIME
ID FLIG_RHIME Reviewed; 345 AA.
AC O54244;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 24-OCT-2001, sequence version 2.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Flagellar motor switch protein FliG;
GN Name=fliG; OrderedLocusNames=R00651; ORFNames=SMc03019;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=RU11/001;
RX PubMed=9858749; DOI=10.1016/s0378-1119(98)00160-7;
RA Sourjik V., Sterr W., Platzer J., Bos I., Haslbeck M., Schmitt R.;
RT "Mapping of 41 chemotaxis, flagellar and motility genes to a single region
RT of the Sinorhizobium meliloti chromosome.";
RL Gene 223:283-290(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: FliG is one of three proteins (FliG, FliN, FliM) that forms
CC the rotor-mounted switch complex (C ring), located at the base of the
CC basal body. This complex interacts with the CheY and CheZ chemotaxis
CC proteins, in addition to contacting components of the motor that
CC determine the direction of flagellar rotation (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Peripheral
CC membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.
CC Bacterial flagellum basal body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FliG family. {ECO:0000305}.
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DR EMBL; AJ224445; CAA11952.1; -; Genomic_DNA.
DR EMBL; AL591688; CAC45223.1; -; Genomic_DNA.
DR RefSeq; NP_384757.1; NC_003047.1.
DR RefSeq; WP_003529920.1; NC_003047.1.
DR AlphaFoldDB; O54244; -.
DR SMR; O54244; -.
DR STRING; 266834.SMc03019; -.
DR EnsemblBacteria; CAC45223; CAC45223; SMc03019.
DR GeneID; 61602118; -.
DR KEGG; sme:SMc03019; -.
DR PATRIC; fig|266834.11.peg.2025; -.
DR eggNOG; COG1536; Bacteria.
DR HOGENOM; CLU_047835_0_1_5; -.
DR OMA; YRKNEEF; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR InterPro; IPR000090; Flg_Motor_Flig.
DR InterPro; IPR023087; Flg_Motor_Flig_C.
DR InterPro; IPR011002; FliG_a-hlx.
DR InterPro; IPR032779; FliG_M.
DR InterPro; IPR028263; FliG_N.
DR PANTHER; PTHR30534; PTHR30534; 1.
DR Pfam; PF01706; FliG_C; 1.
DR Pfam; PF14841; FliG_M; 1.
DR Pfam; PF14842; FliG_N; 1.
DR PRINTS; PR00954; FLGMOTORFLIG.
DR SUPFAM; SSF48029; SSF48029; 2.
PE 3: Inferred from homology;
KW Bacterial flagellum; Cell inner membrane; Cell membrane; Chemotaxis;
KW Flagellar rotation; Membrane; Reference proteome.
FT CHAIN 1..345
FT /note="Flagellar motor switch protein FliG"
FT /id="PRO_0000184093"
FT MOTIF 139..142
FT /note="Part of the EHPQR-motif"
FT SITE 174
FT /note="Part of the EHPQR-motif"
FT CONFLICT 156
FT /note="G -> C (in Ref. 1; CAA11952)"
FT /evidence="ECO:0000305"
FT CONFLICT 183
FT /note="P -> A (in Ref. 1; CAA11952)"
FT /evidence="ECO:0000305"
FT CONFLICT 202..203
FT /note="AD -> TE (in Ref. 1; CAA11952)"
FT /evidence="ECO:0000305"
FT CONFLICT 239
FT /note="V -> A (in Ref. 1; CAA11952)"
FT /evidence="ECO:0000305"
FT CONFLICT 269
FT /note="T -> A (in Ref. 1; CAA11952)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 345 AA; 37740 MW; 28BE9FE40B7A3074 CRC64;
MTDFGSFEAQ AQALAQPLSQ TEKAAAVLLA MGKSIAGKLL KFFTQSELQA IIAAAQSLRA
VPPHELEALV NEFEDLFTEG AGLMDNAKAM ESILEEGLTP DEVDGLLGRR ATFQSYEASI
WDRLMDCDPV IIAQLLAREH PQTIAYVLSM MPSSFGAKVL LQLSDKQRPE ILNRAVNIKN
VNPKAAAIIE ARVIEIIEEM EADRNSPGPA KIAEVMNELE KPQVDTLLAS LETISTDSVK
KVRPKIFLFD DILFMPQRSR VQLFNDVSTD VITMALRGSA AELRESILAS IGARQRRMIE
SDLAAGDAGI NPRDIAIARR SITQEAIRLS ASGQLELKEK EPEAA
