ID   FLIG_SALTY              Reviewed;         331 AA.
AC   P0A1J9; P15933;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Flagellar motor switch protein FliG;
GN   Name=fliG; Synonyms=fla AII.2, fla BII; OrderedLocusNames=STM1970;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2656645; DOI=10.1128/jb.171.6.3247-3257.1989;
RA   Kihara M., Homma M., Kutsukake K., Macnab R.M.;
RT   "Flagellar switch of Salmonella typhimurium: gene sequences and deduced
RT   protein sequences.";
RL   J. Bacteriol. 171:3247-3257(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 297-331.
RX   PubMed=1646201; DOI=10.1128/jb.173.11.3564-3572.1991;
RA   Vogler A.P., Homma M., Irikura V.M., Macnab R.M.;
RT   "Salmonella typhimurium mutants defective in flagellar filament regrowth
RT   and sequence similarity of FliI to F0F1, vacuolar, and archaebacterial
RT   ATPase subunits.";
RL   J. Bacteriol. 173:3564-3572(1991).
RN   [4]
RP   SUBCELLULAR LOCATION.
RX   PubMed=1631122; DOI=10.1073/pnas.89.14.6304;
RA   Francis N.R., Irikura V.M., Yamaguchi S., Derosier D.J., Macnab R.M.;
RT   "Localization of the Salmonella typhimurium flagellar switch protein FliG
RT   to the cytoplasmic M-ring face of the basal body.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:6304-6308(1992).
CC   -!- FUNCTION: FliG is one of three proteins (FliG, FliN, FliM) that forms
CC       the rotor-mounted switch complex (C ring), located at the base of the
CC       basal body. This complex interacts with the CheY and CheZ chemotaxis
CC       proteins, in addition to contacting components of the motor that
CC       determine the direction of flagellar rotation (By similarity).
CC       {ECO:0000250}.
CC   -!- INTERACTION:
CC       P0A1J9; P15928: fliF; NbExp=4; IntAct=EBI-2012130, EBI-2012119;
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:1631122};
CC       Peripheral membrane protein {ECO:0000269|PubMed:1631122}; Cytoplasmic
CC       side {ECO:0000269|PubMed:1631122}. Bacterial flagellum basal body
CC       {ECO:0000269|PubMed:1631122}.
CC   -!- SIMILARITY: Belongs to the FliG family. {ECO:0000305}.
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DR   EMBL; M24462; AAA27097.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20882.1; -; Genomic_DNA.
DR   EMBL; M62408; AAA27099.1; -; Genomic_DNA.
DR   PIR; A44513; A30929.
DR   RefSeq; NP_460923.1; NC_003197.2.
DR   RefSeq; WP_000067735.1; NC_003197.2.
DR   AlphaFoldDB; P0A1J9; -.
DR   SMR; P0A1J9; -.
DR   IntAct; P0A1J9; 1.
DR   STRING; 99287.STM1970; -.
DR   PaxDb; P0A1J9; -.
DR   EnsemblBacteria; AAL20882; AAL20882; STM1970.
DR   GeneID; 1253491; -.
DR   KEGG; stm:STM1970; -.
DR   PATRIC; fig|99287.12.peg.2087; -.
DR   HOGENOM; CLU_047835_2_0_6; -.
DR   OMA; QVRPFEF; -.
DR   PhylomeDB; P0A1J9; -.
DR   BioCyc; SENT99287:STM1970-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IMP:CACAO.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   InterPro; IPR000090; Flg_Motor_Flig.
DR   InterPro; IPR023087; Flg_Motor_Flig_C.
DR   InterPro; IPR011002; FliG_a-hlx.
DR   InterPro; IPR032779; FliG_M.
DR   InterPro; IPR028263; FliG_N.
DR   PANTHER; PTHR30534; PTHR30534; 1.
DR   Pfam; PF01706; FliG_C; 1.
DR   Pfam; PF14841; FliG_M; 1.
DR   Pfam; PF14842; FliG_N; 1.
DR   PIRSF; PIRSF003161; FliG; 1.
DR   PRINTS; PR00954; FLGMOTORFLIG.
DR   SUPFAM; SSF48029; SSF48029; 2.
DR   TIGRFAMs; TIGR00207; fliG; 1.
PE   1: Evidence at protein level;
KW   Bacterial flagellum; Cell inner membrane; Cell membrane; Chemotaxis;
KW   Flagellar rotation; Membrane; Reference proteome.
FT   CHAIN           1..331
FT                   /note="Flagellar motor switch protein FliG"
FT                   /id="PRO_0000184095"
FT   MOTIF           125..128
FT                   /note="Part of the EHPQR-motif"
FT   SITE            160
FT                   /note="Part of the EHPQR-motif"
SQ   SEQUENCE   331 AA;  36851 MW;  C78CFA01AED9B010 CRC64;
     MSNLSGTDKS VILLMTIGED RAAEVFKHLS TREVQALSTA MANVRQISNK QLTDVLSEFE
     QEAEQFAALN INANEYLRSV LVKALGEERA SSLLEDILET RDTTSGIETL NFMEPQSAAD
     LIRDEHPQII ATILVHLKRS QAADILALFD ERLRHDVMLR IATFGGVQPA ALAELTEVLN
     GLLDGQNLKR SKMGGVRTAA EIINLMKTQQ EEAVITAVRE FDGELAQKII DEMFLFENLV
     DVDDRSIQRL LQEVDSESLL IALKGAEPPL REKFLRNMSQ RAADILRDDL ANRGPVRLSQ
     VENEQKAILL IVRRLAETGE MVIGSGEDTY V