ID   FLIH_ECOLI              Reviewed;         228 AA.
AC   P31068; P76325;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 3.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Flagellar assembly protein FliH;
GN   Name=fliH; Synonyms=fla AII.3, fla BIII; OrderedLocusNames=b1940, JW1924;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA   Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA   Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA   Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA   Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA   Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA   Horiuchi T.;
RT   "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 40.1-50.0 min region on the linkage map.";
RL   DNA Res. 3:379-392(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-14.
RX   PubMed=8224881; DOI=10.1016/0378-1119(93)90232-r;
RA   Roman S.J., Frantz B.B., Matsumura P.;
RT   "Gene sequence, overproduction, purification and determination of the wild-
RT   type level of the Escherichia coli flagellar switch protein FliG.";
RL   Gene 133:103-108(1993).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 197-228.
RC   STRAIN=K12;
RA   Macnab R.M.;
RL   Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Needed for flagellar regrowth and assembly.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the FliH family. {ECO:0000305}.
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DR   EMBL; U00096; AAC75007.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15765.1; -; Genomic_DNA.
DR   EMBL; L13243; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; L49147; AAA82636.1; -; Genomic_DNA.
DR   PIR; A64958; A64958.
DR   RefSeq; NP_416450.2; NC_000913.3.
DR   RefSeq; WP_001282683.1; NZ_LN832404.1.
DR   AlphaFoldDB; P31068; -.
DR   SMR; P31068; -.
DR   BioGRID; 4260385; 23.
DR   ComplexPortal; CPX-5885; Flagellar export complex.
DR   DIP; DIP-9654N; -.
DR   IntAct; P31068; 12.
DR   STRING; 511145.b1940; -.
DR   PaxDb; P31068; -.
DR   PRIDE; P31068; -.
DR   EnsemblBacteria; AAC75007; AAC75007; b1940.
DR   EnsemblBacteria; BAA15765; BAA15765; BAA15765.
DR   GeneID; 946456; -.
DR   KEGG; ecj:JW1924; -.
DR   KEGG; eco:b1940; -.
DR   PATRIC; fig|1411691.4.peg.311; -.
DR   EchoBASE; EB1608; -.
DR   eggNOG; COG1317; Bacteria.
DR   HOGENOM; CLU_062625_4_2_6; -.
DR   InParanoid; P31068; -.
DR   OMA; WALPSFD; -.
DR   PhylomeDB; P31068; -.
DR   BioCyc; EcoCyc:EG11656-MON; -.
DR   PRO; PR:P31068; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0009288; C:bacterial-type flagellum; IC:ComplexPortal.
DR   GO; GO:0120102; C:bacterial-type flagellum secretion apparatus; IC:ComplexPortal.
DR   GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR   GO; GO:0030257; C:type III protein secretion system complex; IC:ComplexPortal.
DR   GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IC:ComplexPortal.
DR   GO; GO:0006935; P:chemotaxis; IC:ComplexPortal.
DR   GO; GO:0030254; P:protein secretion by the type III secretion system; IC:ComplexPortal.
DR   InterPro; IPR000563; Flag_FliH.
DR   InterPro; IPR018035; Flagellar_FliH/T3SS_HrpE.
DR   Pfam; PF02108; FliH; 1.
DR   PRINTS; PR01003; FLGFLIH.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Bacterial flagellum protein export;
KW   Cytoplasm; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..228
FT                   /note="Flagellar assembly protein FliH"
FT                   /id="PRO_0000180893"
FT   CONFLICT        3
FT                   /note="D -> N (in Ref. 4; L13243)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   228 AA;  25050 MW;  DF49BC3C0456552A CRC64;
     MSDNLPWKTW TPDDLAPPQA EFVPIVEPEE TIIEEAEPSL EQQLAQLQMQ AHEQGYQAGI
     AEGRQQGHKQ GYQEGLAQGL EQGLAEAKSQ QAPIHARMQQ LVSEFQTTLD ALDSVIASRL
     MQMALEAARQ VIGQTPTVDN SALIKQIQQL LQQEPLFSGK PQLRVHPDDL QRVDDMLGAT
     LSLHGWRLRG DPTLHPGGCK VSADEGDLDA SVATRWQELC RLAAPGVV