FLIH_SALTY
ID FLIH_SALTY Reviewed; 235 AA.
AC P15934;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 2.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Flagellar assembly protein FliH;
GN Name=fliH; Synonyms=fla AII.3, fla BIII; OrderedLocusNames=STM1971;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1646201; DOI=10.1128/jb.173.11.3564-3572.1991;
RA Vogler A.P., Homma M., Irikura V.M., Macnab R.M.;
RT "Salmonella typhimurium mutants defective in flagellar filament regrowth
RT and sequence similarity of FliI to F0F1, vacuolar, and archaebacterial
RT ATPase subunits.";
RL J. Bacteriol. 173:3564-3572(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-10.
RX PubMed=2656645; DOI=10.1128/jb.171.6.3247-3257.1989;
RA Kihara M., Homma M., Kutsukake K., Macnab R.M.;
RT "Flagellar switch of Salmonella typhimurium: gene sequences and deduced
RT protein sequences.";
RL J. Bacteriol. 171:3247-3257(1989).
CC -!- FUNCTION: Needed for flagellar regrowth and assembly.
CC -!- INTERACTION:
CC P15934; P40729: flhA; NbExp=2; IntAct=EBI-6410310, EBI-6410261;
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the FliH family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; M62408; AAA27100.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20883.1; -; Genomic_DNA.
DR EMBL; M24462; AAA27098.1; -; Genomic_DNA.
DR PIR; B42364; B42364.
DR RefSeq; NP_460924.1; NC_003197.2.
DR RefSeq; WP_000064163.1; NC_003197.2.
DR PDB; 5B0O; X-ray; 3.00 A; E/F/G/H/I/J/K/L=99-235.
DR PDBsum; 5B0O; -.
DR AlphaFoldDB; P15934; -.
DR SMR; P15934; -.
DR IntAct; P15934; 2.
DR STRING; 99287.STM1971; -.
DR TCDB; 3.A.6.2.1; the type iii (virulence-related) secretory pathway (iiisp) family.
DR PaxDb; P15934; -.
DR EnsemblBacteria; AAL20883; AAL20883; STM1971.
DR GeneID; 1253492; -.
DR KEGG; stm:STM1971; -.
DR PATRIC; fig|99287.12.peg.2088; -.
DR HOGENOM; CLU_062625_4_2_6; -.
DR OMA; WALPSFD; -.
DR PhylomeDB; P15934; -.
DR BioCyc; SENT99287:STM1971-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0009288; C:bacterial-type flagellum; IEA:InterPro.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR000563; Flag_FliH.
DR InterPro; IPR018035; Flagellar_FliH/T3SS_HrpE.
DR Pfam; PF02108; FliH; 1.
DR PRINTS; PR01003; FLGFLIH.
PE 1: Evidence at protein level;
KW 3D-structure; Bacterial flagellum biogenesis;
KW Bacterial flagellum protein export; Cytoplasm; Protein transport;
KW Reference proteome; Transport.
FT CHAIN 1..235
FT /note="Flagellar assembly protein FliH"
FT /id="PRO_0000180894"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT HELIX 101..141
FT /evidence="ECO:0007829|PDB:5B0O"
FT HELIX 148..158
FT /evidence="ECO:0007829|PDB:5B0O"
FT STRAND 169..172
FT /evidence="ECO:0007829|PDB:5B0O"
FT HELIX 174..190
FT /evidence="ECO:0007829|PDB:5B0O"
FT STRAND 194..197
FT /evidence="ECO:0007829|PDB:5B0O"
FT STRAND 207..209
FT /evidence="ECO:0007829|PDB:5B0O"
FT STRAND 214..216
FT /evidence="ECO:0007829|PDB:5B0O"
FT HELIX 219..230
FT /evidence="ECO:0007829|PDB:5B0O"
SQ SEQUENCE 235 AA; 25811 MW; 3878ACD47C5D7749 CRC64;
MSNELPWQVW TPDDLAPPPE TFVPVEADNV TLTEDTPEPE LTAEQQLEQE LAQLKIQAHE
QGYNAGLAEG RQKGHAQGYQ EGLAQGLEQG QAQAQTQQAP IHARMQQLVS EFQNTLDALD
SVIASRLMQM ALEAARQVIG QTPAVDNSAL IKQIQQLLQQ EPLFSGKPQL RVHPDDLQRV
EEMLGATLSL HGWRLRGDPT LHHGGCKVSA DEGDLDASVA TRWQELCRLA APGVL
