ID   FLII_AQUAE              Reviewed;         443 AA.
AC   O67531;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=Flagellum-specific ATP synthase;
DE            EC=7.1.2.2;
GN   Name=fliI; OrderedLocusNames=aq_1595;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Probable catalytic subunit of a protein translocase for
CC       flagellum-specific export, or a proton translocase involved in local
CC       circuits at the flagellum. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate;
CC         Xref=Rhea:RHEA:57720, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.1.2.2;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU10106};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ATPase alpha/beta chains family.
CC       {ECO:0000305}.
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DR   EMBL; AE000657; AAC07494.1; -; Genomic_DNA.
DR   PIR; A70438; A70438.
DR   RefSeq; NP_214096.1; NC_000918.1.
DR   RefSeq; WP_010881034.1; NC_000918.1.
DR   AlphaFoldDB; O67531; -.
DR   SMR; O67531; -.
DR   STRING; 224324.aq_1595; -.
DR   EnsemblBacteria; AAC07494; AAC07494; aq_1595.
DR   KEGG; aae:aq_1595; -.
DR   PATRIC; fig|224324.8.peg.1231; -.
DR   eggNOG; COG1157; Bacteria.
DR   HOGENOM; CLU_022398_5_1_0; -.
DR   InParanoid; O67531; -.
DR   OMA; MLMMDSV; -.
DR   OrthoDB; 875807at2; -.
DR   BRENDA; 7.4.2.8; 396.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IBA:GO_Central.
DR   GO; GO:0030257; C:type III protein secretion system complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-EC.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:UniProtKB-EC.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR020003; ATPase_a/bsu_AS.
DR   InterPro; IPR004100; ATPase_F1/V1/A1_a/bsu_N.
DR   InterPro; IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
DR   InterPro; IPR005714; ATPase_T3SS_FliI/YscN.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR040627; T3SS_ATPase_C.
DR   Pfam; PF00006; ATP-synt_ab; 1.
DR   Pfam; PF02874; ATP-synt_ab_N; 1.
DR   Pfam; PF18269; T3SS_ATPase_C; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01026; fliI_yscN; 1.
DR   PROSITE; PS00152; ATPASE_ALPHA_BETA; 1.
PE   3: Inferred from homology;
KW   ATP synthesis; ATP-binding; Bacterial flagellum biogenesis;
KW   Bacterial flagellum protein export; Cytoplasm; Hydrogen ion transport;
KW   Ion transport; Nucleotide-binding; Protein transport; Reference proteome;
KW   Translocase; Transport.
FT   CHAIN           1..443
FT                   /note="Flagellum-specific ATP synthase"
FT                   /id="PRO_0000144686"
FT   BINDING         169..176
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   443 AA;  48507 MW;  62D7F5BD7C6B14A0 CRC64;
     MKGIRRNLQK SYLKRCSEMY LRGLKVSGEI VSAKGIYLEA ILPFANIGNE VEIQSNSRRI
     RGEVIGFSGD KVLVMPYEPV FGLRKGDKVL LKNELVSTKT GNGVVGKVVD PFGNPLDGGF
     IGFVEEKGLE LPQINPLYRE RIREVFDTGV RSVNALFTLG KGQKIGIFAG AGVGKSTLLG
     MITRHSKADV VVLALIGERG REVKEFLEEV LGEEGLKKSV VVVSTADQSP ILKVKGAISA
     VVHAHHFASQ GKDVLLLMDS ITRLALAQRE IGLAAGEPPT LKGFTPSVFQ LLTRIAESCG
     AFKKGSITGI FTVLVEGDDI SLDPIADSLM GVLDGHIILS RKRAVRGLFP AVDPVRSLSR
     LMPKLVSEEH FMKANFFKEV LSKFEDVEEL VRIGLYKGGS NPLVDKVINN LEKVESFFKQ
     KPEEKVNFEE SLKALDEIYS LLK