ID   FLIK_BACSU              Reviewed;         487 AA.
AC   P23451;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 2.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Probable flagellar hook-length control protein;
GN   Name=fliK; OrderedLocusNames=BSU16270;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=1828465; DOI=10.1128/jb.173.11.3573-3579.1991;
RA   Albertini A.M., Caramori T., Crabb W.D., Scoffone F., Galizzi A.;
RT   "The flaA locus of Bacillus subtilis is part of a large operon coding for
RT   flagellar structures, motility functions, and an ATPase-like polypeptide.";
RL   J. Bacteriol. 173:3573-3579(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   SEQUENCE REVISION TO 113-115; 268 AND N-TERMINUS.
RX   PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA   Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA   Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT   "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT   168 reference genome a decade later.";
RL   Microbiology 155:1758-1775(2009).
CC   -!- FUNCTION: Controls the length of the flagellar hook. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FliK family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X56049; CAA39526.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB13500.2; -; Genomic_DNA.
DR   PIR; G42365; G42365.
DR   RefSeq; NP_389509.2; NC_000964.3.
DR   RefSeq; WP_003231973.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; P23451; -.
DR   SMR; P23451; -.
DR   STRING; 224308.BSU16270; -.
DR   PaxDb; P23451; -.
DR   PRIDE; P23451; -.
DR   EnsemblBacteria; CAB13500; CAB13500; BSU_16270.
DR   GeneID; 937494; -.
DR   KEGG; bsu:BSU16270; -.
DR   PATRIC; fig|224308.179.peg.1767; -.
DR   eggNOG; COG3144; Bacteria.
DR   InParanoid; P23451; -.
DR   OMA; NGMFQSK; -.
DR   BioCyc; BSUB:BSU16270-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:InterPro.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IMP:CACAO.
DR   GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IMP:CACAO.
DR   Gene3D; 3.30.750.140; -; 1.
DR   InterPro; IPR001635; Flag_hook_Flik.
DR   InterPro; IPR021136; Flagellar_hook_control-like_C.
DR   InterPro; IPR038610; FliK-like_C_sf.
DR   Pfam; PF02120; Flg_hook; 1.
DR   PRINTS; PR01007; FLGHOOKFLIK.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Reference proteome.
FT   CHAIN           1..487
FT                   /note="Probable flagellar hook-length control protein"
FT                   /id="PRO_0000180904"
FT   REGION          144..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          286..311
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          447..487
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        456..472
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        1..60
FT                   /note="MKLLELAGPLLQTTTGSAAKNMKSSQGVFQNWLMSEAGLKELSEQGKGTPNS
FT                   EDQLLADA -> MR (in Ref. 1; CAA39526)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        113..115
FT                   /note="MSG -> NVS (in Ref. 1; CAA39526)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        268
FT                   /note="S -> T (in Ref. 1; CAA39526)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   487 AA;  53533 MW;  DA8528AD1E1E7772 CRC64;
     MKLLELAGPL LQTTTGSAAK NMKSSQGVFQ NWLMSEAGLK ELSEQGKGTP NSEDQLLADA
     LKKIGEWLNA SPEDQDKQNA DLLQTLSKLT GKQLDANALQ MLQNLLQAVE SKMSGGTDQL
     LTETEKIFSE AKTALSANDS ASDINGALKS DKEQSNQENE VSEPAKELIY IQMFISQLVE
     GNKLTDLGNG NEAHAIYQNG DQFLSALEKK GVSQQLIQDL KQQIFTKAES SSKLYSMTAS
     ELKSFQSLMD QMSMLPQKGT KEWSLAESQL KAFLLSKSSE SSQDFGKSVL TPLSQSSSSK
     NASDVSGSIQ PVDSKSGLQM LFSGYRGIGG VQTLDLQQMS SDIPNAETKT VADQVINAWK
     QMKYTPFGRS TGSFTIRLNP EHLGFVTIKL TNENGMFQSK IIASSQSAKE LLEQHLPQLK
     QSLPNMAVQI DRFTLPVQSG DQPIYGQLAD EQKQQQEGQR QQRQKKQSND FGDLLDEVSM
     VEMEEEE