ID   FLIM_CAUVN              Reviewed;         374 AA.
AC   B8GXB5; P34009;
DT   13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Flagellar motor switch protein FliM;
GN   Name=fliM; Synonyms=flbO; OrderedLocusNames=CCNA_02140;
OS   Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=565050;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1315735; DOI=10.1128/jb.174.10.3327-3338.1992;
RA   Yu J., Shapiro L.;
RT   "Early Caulobacter crescentus genes fliL and fliM are required for
RT   flagellar gene expression and normal cell division.";
RL   J. Bacteriol. 174:3327-3338(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA1000 / CB15N;
RX   PubMed=20472802; DOI=10.1128/jb.00255-10;
RA   Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V.,
RA   Walunas T.L., Crosson S.;
RT   "The genetic basis of laboratory adaptation in Caulobacter crescentus.";
RL   J. Bacteriol. 192:3678-3688(2010).
CC   -!- FUNCTION: FliM is one of three proteins (FliG, FliN, FliM) that forms
CC       the rotor-mounted switch complex (C ring), located at the base of the
CC       basal body. This complex interacts with the CheY and CheZ chemotaxis
CC       proteins, in addition to contacting components of the motor that
CC       determine the direction of flagellar rotation (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein.
CC       Bacterial flagellum basal body {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FliM family. {ECO:0000305}.
CC   -!- CAUTION: It is uncertain whether Met-1, Met-11, Val-26 or Met-36 is the
CC       initiator. {ECO:0000305}.
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DR   EMBL; M85232; AAA62449.1; -; Genomic_DNA.
DR   EMBL; CP001340; ACL95605.1; -; Genomic_DNA.
DR   RefSeq; WP_012640397.1; NC_011916.1.
DR   RefSeq; YP_002517513.1; NC_011916.1.
DR   AlphaFoldDB; B8GXB5; -.
DR   SMR; B8GXB5; -.
DR   PRIDE; B8GXB5; -.
DR   EnsemblBacteria; ACL95605; ACL95605; CCNA_02140.
DR   GeneID; 7330446; -.
DR   KEGG; ccs:CCNA_02140; -.
DR   PATRIC; fig|565050.3.peg.2098; -.
DR   HOGENOM; CLU_052646_2_0_5; -.
DR   OMA; NPQFTQI; -.
DR   OrthoDB; 1748746at2; -.
DR   PhylomeDB; B8GXB5; -.
DR   Proteomes; UP000001364; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR   GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   CDD; cd17908; FliM; 1.
DR   Gene3D; 2.30.330.10; -; 1.
DR   Gene3D; 3.40.1550.10; -; 1.
DR   InterPro; IPR028976; CheC-like_sf.
DR   InterPro; IPR001689; Flag_FliM.
DR   InterPro; IPR001543; FliN-like_C.
DR   InterPro; IPR036429; SpoA-like_sf.
DR   Pfam; PF02154; FliM; 1.
DR   Pfam; PF01052; FliMN_C; 1.
DR   PIRSF; PIRSF002888; FliM; 1.
DR   PRINTS; PR00955; FLGMOTORFLIM.
DR   SUPFAM; SSF101801; SSF101801; 1.
DR   SUPFAM; SSF103039; SSF103039; 1.
DR   TIGRFAMs; TIGR01397; fliM_switch; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Cell inner membrane; Cell membrane; Chemotaxis;
KW   Flagellar rotation; Membrane; Reference proteome.
FT   CHAIN           1..374
FT                   /note="Flagellar motor switch protein FliM"
FT                   /id="PRO_0000395337"
FT   REGION          1..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        139
FT                   /note="A -> G (in Ref. 1; AAA62449)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        199
FT                   /note="E -> D (in Ref. 1; AAA62449)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        227
FT                   /note="R -> P (in Ref. 1; AAA62449)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        329..339
FT                   /note="PDSLVELRAGA -> SRQPGGAARRR (in Ref. 1; AAA62449)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        362..366
FT                   /note="LTPAA -> VDRR (in Ref. 1; AAA62449)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   374 AA;  41261 MW;  03D0E6E3710904AA CRC64;
     MADELDDQAA MAQWASENPP GGGEGVNEFG DFSGGMGGWD DGGGDGASER ILNQDEIDSL
     LGFDLSGDGS DDRTGIRAII NSALVSYERL PMLEIVFDRL VRLMTTSLRN FTSDNVEVSL
     DNISSIRFGD YLNSIPLPAI LAVFRAEELD NYGLLTVDSN LIYSIVDVLL GGRRGTAAMR
     IEGRPYTTIE RVLVQRMIEV VLHDLKSAFE PLHPVSFSLD RLETNPRFAA IARPANAAIL
     VKLRIDMEDR GGRIELLLPY ATLEPIRKML LQQFMGEKFG RDNIWEGHLA TELWTTQMEV
     RAVLDEQQVP LSRVLNMQVG DTLMLNATPD SLVELRAGAI PLTRGRMGRR NHSIAVRAEA
     PLTPAAKKAV QKLK