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FLIN_ECOLI
ID   FLIN_ECOLI              Reviewed;         137 AA.
AC   P15070;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   25-MAY-2022, entry version 155.
DE   RecName: Full=Flagellar motor switch protein FliN;
GN   Name=fliN; Synonyms=flaN, motD; OrderedLocusNames=b1946, JW1930;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=2651416; DOI=10.1128/jb.171.5.2728-2734.1989;
RA   Malakooti J., Komeda Y., Matsumura P.;
RT   "DNA sequence analysis, gene product identification, and localization of
RT   flagellar motor components of Escherichia coli.";
RL   J. Bacteriol. 171:2728-2734(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA   Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA   Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA   Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA   Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA   Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA   Horiuchi T.;
RT   "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 40.1-50.0 min region on the linkage map.";
RL   DNA Res. 3:379-392(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   REVIEW.
RX   PubMed=19081534; DOI=10.1016/s1937-6448(08)01402-0;
RA   Terashima H., Kojima S., Homma M.;
RT   "Flagellar motility in bacteria structure and function of flagellar
RT   motor.";
RL   Int. Rev. Cytol. 270:39-85(2008).
CC   -!- FUNCTION: FliN is one of three proteins (FliG, FliN, FliM) that form a
CC       switch complex that is proposed to be located at the base of the basal
CC       body. This complex interacts with the CheY and CheZ chemotaxis
CC       proteins, in addition to contacting components of the motor that
CC       determine the direction of flagellar rotation.
CC   -!- INTERACTION:
CC       P15070; P06974: fliM; NbExp=7; IntAct=EBI-2011987, EBI-560439;
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein;
CC       Cytoplasmic side. Bacterial flagellum basal body.
CC   -!- SIMILARITY: Belongs to the FliN/MopA/SpaO family. {ECO:0000305}.
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DR   EMBL; M26294; AAA03207.1; -; Unassigned_DNA.
DR   EMBL; U00096; AAC75013.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15771.1; -; Genomic_DNA.
DR   PIR; JS0111; XMECII.
DR   RefSeq; NP_416456.1; NC_000913.3.
DR   RefSeq; WP_001282101.1; NZ_LN832404.1.
DR   AlphaFoldDB; P15070; -.
DR   SMR; P15070; -.
DR   BioGRID; 4261042; 381.
DR   BioGRID; 850780; 3.
DR   ComplexPortal; CPX-1082; Flagellar Motor Switch Complex, CW variant.
DR   ComplexPortal; CPX-1085; Flagellar Motor Switch Complex, CCW variant.
DR   DIP; DIP-1101N; -.
DR   IntAct; P15070; 10.
DR   STRING; 511145.b1946; -.
DR   PaxDb; P15070; -.
DR   PRIDE; P15070; -.
DR   EnsemblBacteria; AAC75013; AAC75013; b1946.
DR   EnsemblBacteria; BAA15771; BAA15771; BAA15771.
DR   GeneID; 946423; -.
DR   KEGG; ecj:JW1930; -.
DR   KEGG; eco:b1946; -.
DR   PATRIC; fig|1411691.4.peg.305; -.
DR   EchoBASE; EB0320; -.
DR   eggNOG; COG1886; Bacteria.
DR   HOGENOM; CLU_097058_1_1_6; -.
DR   InParanoid; P15070; -.
DR   OMA; THNDIDM; -.
DR   PhylomeDB; P15070; -.
DR   BioCyc; EcoCyc:FLIN-FLAGELLAR-C-RING-SWITCH; -.
DR   PRO; PR:P15070; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0009288; C:bacterial-type flagellum; IC:ComplexPortal.
DR   GO; GO:0009433; C:bacterial-type flagellum basal body, C ring; IC:ComplexPortal.
DR   GO; GO:0120107; C:bacterial-type flagellum rotor complex; IC:ComplexPortal.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR   GO; GO:0071977; P:bacterial-type flagellum-dependent swimming motility; IC:ComplexPortal.
DR   GO; GO:0006935; P:chemotaxis; IC:ComplexPortal.
DR   Gene3D; 2.30.330.10; -; 1.
DR   InterPro; IPR012826; FliN.
DR   InterPro; IPR001543; FliN-like_C.
DR   InterPro; IPR031576; FliN_N.
DR   InterPro; IPR001172; FliN_T3SS_HrcQb.
DR   InterPro; IPR036429; SpoA-like_sf.
DR   Pfam; PF01052; FliMN_C; 1.
DR   Pfam; PF16973; FliN_N; 1.
DR   PRINTS; PR00956; FLGMOTORFLIN.
DR   SUPFAM; SSF101801; SSF101801; 1.
DR   TIGRFAMs; TIGR02480; fliN; 1.
PE   1: Evidence at protein level;
KW   Bacterial flagellum; Cell inner membrane; Cell membrane; Chemotaxis;
KW   Flagellar rotation; Membrane; Reference proteome.
FT   CHAIN           1..137
FT                   /note="Flagellar motor switch protein FliN"
FT                   /id="PRO_0000184118"
SQ   SEQUENCE   137 AA;  14855 MW;  93A77AE3FEF33091 CRC64;
     MSDMNNPADD NNGAMDDLWA EALSEQKSTS SKSAAETVFQ QFGGGDVSGT LQDIDLIMDI
     PVKLTVELGR TRMTIKELLR LTQGSVVALD GLAGEPLDIL INGYLIAQGE VVVVADKYGV
     RITDIITPSE RMRRLSR
 
 
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