FLIN_SALTY
ID FLIN_SALTY Reviewed; 137 AA.
AC P26419;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Flagellar motor switch protein FliN;
GN Name=fliN; Synonyms=flaN, motD; OrderedLocusNames=STM1977;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2656645; DOI=10.1128/jb.171.6.3247-3257.1989;
RA Kihara M., Homma M., Kutsukake K., Macnab R.M.;
RT "Flagellar switch of Salmonella typhimurium: gene sequences and deduced
RT protein sequences.";
RL J. Bacteriol. 171:3247-3257(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 106-137.
RC STRAIN=LT2;
RX PubMed=9324257; DOI=10.1128/jb.179.19.6092-6099.1997;
RA Ohnishi K., Fan F., Schoenhals G.J., Kihara M., Macnab R.M.;
RT "The FliO, FliP, FliQ, and FliR proteins of Salmonella typhimurium:
RT putative components for flagellar assembly.";
RL J. Bacteriol. 179:6092-6099(1997).
CC -!- FUNCTION: FliN is one of three proteins (FliG, FliN, FliM) that form
CC the rotor-mounted switch complex (C ring), located at the base of the
CC basal body. This complex interacts with the CheY and CheZ chemotaxis
CC proteins, in addition to contacting components of the motor that
CC determine the direction of flagellar rotation (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein;
CC Cytoplasmic side. Bacterial flagellum basal body.
CC -!- SIMILARITY: Belongs to the FliN/MopA/SpaO family. {ECO:0000305}.
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DR EMBL; M24463; AAA27105.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20889.1; -; Genomic_DNA.
DR EMBL; L49021; AAB81317.1; -; Genomic_DNA.
DR PIR; D44513; D30929.
DR RefSeq; NP_460930.1; NC_003197.2.
DR RefSeq; WP_001282115.1; NC_003197.2.
DR PDB; 4YXB; X-ray; 2.56 A; A/B=5-137, C=38-43, D=67-137.
DR PDB; 4YXC; X-ray; 2.30 A; B=5-137.
DR PDBsum; 4YXB; -.
DR PDBsum; 4YXC; -.
DR AlphaFoldDB; P26419; -.
DR SMR; P26419; -.
DR IntAct; P26419; 1.
DR STRING; 99287.STM1977; -.
DR TCDB; 3.A.6.2.1; the type iii (virulence-related) secretory pathway (iiisp) family.
DR PaxDb; P26419; -.
DR EnsemblBacteria; AAL20889; AAL20889; STM1977.
DR GeneID; 1253498; -.
DR GeneID; 66756494; -.
DR KEGG; stm:STM1977; -.
DR PATRIC; fig|99287.12.peg.2094; -.
DR HOGENOM; CLU_097058_1_1_6; -.
DR OMA; THNDIDM; -.
DR PhylomeDB; P26419; -.
DR BioCyc; SENT99287:STM1977-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:InterPro.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR Gene3D; 2.30.330.10; -; 1.
DR InterPro; IPR012826; FliN.
DR InterPro; IPR001543; FliN-like_C.
DR InterPro; IPR031576; FliN_N.
DR InterPro; IPR001172; FliN_T3SS_HrcQb.
DR InterPro; IPR036429; SpoA-like_sf.
DR Pfam; PF01052; FliMN_C; 1.
DR Pfam; PF16973; FliN_N; 1.
DR PRINTS; PR00956; FLGMOTORFLIN.
DR SUPFAM; SSF101801; SSF101801; 1.
DR TIGRFAMs; TIGR02480; fliN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Bacterial flagellum; Cell inner membrane; Cell membrane;
KW Chemotaxis; Flagellar rotation; Membrane; Reference proteome.
FT CHAIN 1..137
FT /note="Flagellar motor switch protein FliN"
FT /id="PRO_0000184119"
FT HELIX 56..59
FT /evidence="ECO:0007829|PDB:4YXB"
FT STRAND 61..73
FT /evidence="ECO:0007829|PDB:4YXC"
FT HELIX 75..79
FT /evidence="ECO:0007829|PDB:4YXC"
FT STRAND 86..92
FT /evidence="ECO:0007829|PDB:4YXC"
FT STRAND 97..101
FT /evidence="ECO:0007829|PDB:4YXC"
FT STRAND 104..114
FT /evidence="ECO:0007829|PDB:4YXC"
FT STRAND 117..125
FT /evidence="ECO:0007829|PDB:4YXC"
FT HELIX 128..136
FT /evidence="ECO:0007829|PDB:4YXC"
SQ SEQUENCE 137 AA; 14789 MW; FDEEAB1F0822FA90 CRC64;
MSDMNNPSDE NTGALDDLWA DALNEQKATT TKSAADAVFQ QLGGGDVSGA MQDIDLIMDI
PVKLTVELGR TRMTIKELLR LTQGSVVALD GLAGEPLDIL INGYLIAQGE VVVVADKYGV
RITDIITPSE RMRRLSR
