FLIP_CAUVC
ID FLIP_CAUVC Reviewed; 266 AA.
AC Q45980;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Flagellar biosynthetic protein FliP;
GN Name=fliP; OrderedLocusNames=CC_0951;
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=7601828; DOI=10.1128/jb.177.13.3656-3667.1995;
RA Gober J.W., Boyd C.H., Jarvis M., Mangan E.K., Rizzo M.F., Wingrove J.A.;
RT "Temporal and spatial regulation of fliP, an early flagellar gene of
RT Caulobacter crescentus that is required for motility and normal cell
RT division.";
RL J. Bacteriol. 177:3656-3667(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- FUNCTION: May be a component of the flagellum. It is required for
CC normal cell division. May be implicated in the secretion of virulence
CC factors.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}. Bacterial flagellum basal body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FliP/MopC/SpaP family. {ECO:0000305}.
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DR EMBL; U20387; AAA86882.1; -; Genomic_DNA.
DR EMBL; AE005673; AAK22935.1; -; Genomic_DNA.
DR PIR; C87367; C87367.
DR RefSeq; NP_419767.1; NC_002696.2.
DR RefSeq; WP_010918835.1; NC_002696.2.
DR AlphaFoldDB; Q45980; -.
DR SMR; Q45980; -.
DR STRING; 190650.CC_0951; -.
DR EnsemblBacteria; AAK22935; AAK22935; CC_0951.
DR KEGG; ccr:CC_0951; -.
DR PATRIC; fig|190650.5.peg.966; -.
DR eggNOG; COG1338; Bacteria.
DR HOGENOM; CLU_042028_0_0_5; -.
DR OMA; MPPNQIL; -.
DR BioCyc; CAULO:CC0951-MON; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR InterPro; IPR005837; FliP.
DR InterPro; IPR005838; T3SS_IM_P.
DR PANTHER; PTHR30587; PTHR30587; 1.
DR PANTHER; PTHR30587:SF0; PTHR30587:SF0; 1.
DR Pfam; PF00813; FliP; 1.
DR PRINTS; PR00951; FLGBIOSNFLIP.
DR PRINTS; PR01302; TYPE3IMPPROT.
DR TIGRFAMs; TIGR01103; fliP; 1.
DR PROSITE; PS01060; FLIP_1; 1.
DR PROSITE; PS01061; FLIP_2; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum; Bacterial flagellum biogenesis;
KW Bacterial flagellum protein export; Cell membrane; Membrane;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport; Virulence.
FT CHAIN 1..266
FT /note="Flagellar biosynthetic protein FliP"
FT /id="PRO_0000191984"
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 266 AA; 28527 MW; A84F17CB1C65A947 CRC64;
MIRDLFKSVI GAKAEDLRRA AIISVLAAIA CAIMPAAAMA QSAVNINLGT GAGLTERVVQ
LVGLMTVLSL APSIVIMTTS FVRIVVVLGL LRTAIGVQQS PPNPVLISLA LFLTAIVMAP
TFERSYDAGI KPLLDQQMEL PEAFEAASGP VKQFMLSQVD RDDLALFVRL SKIPQPRTAA
ETPLRVVTPA FMISELKRAF EIGFLLFIPF LVIDLVVASV LMSMGMMMLP PASISLPFKL
IFFVLVDGWR LVAGSLVESF QRGAGG