FLIP_ECO57
ID FLIP_ECO57 Reviewed; 245 AA.
AC P0AC06; P33133;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Flagellar biosynthetic protein FliP;
DE Flags: Precursor;
GN Name=fliP; OrderedLocusNames=Z3038, ECs2687;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Plays a role in the flagellum-specific transport system.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}. Bacterial flagellum basal body
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FliP/MopC/SpaP family. {ECO:0000305}.
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DR EMBL; AE005174; AAG56963.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB36110.1; -; Genomic_DNA.
DR PIR; G85812; G85812.
DR PIR; G90964; G90964.
DR RefSeq; NP_310714.1; NC_002695.1.
DR RefSeq; WP_001253441.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P0AC06; -.
DR SMR; P0AC06; -.
DR STRING; 155864.EDL933_2956; -.
DR EnsemblBacteria; AAG56963; AAG56963; Z3038.
DR EnsemblBacteria; BAB36110; BAB36110; ECs_2687.
DR GeneID; 66674162; -.
DR GeneID; 913785; -.
DR KEGG; ece:Z3038; -.
DR KEGG; ecs:ECs_2687; -.
DR PATRIC; fig|386585.9.peg.2815; -.
DR eggNOG; COG1338; Bacteria.
DR HOGENOM; CLU_042028_0_1_6; -.
DR OMA; MPPNQIL; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR InterPro; IPR005837; FliP.
DR InterPro; IPR005838; T3SS_IM_P.
DR PANTHER; PTHR30587; PTHR30587; 1.
DR PANTHER; PTHR30587:SF0; PTHR30587:SF0; 1.
DR Pfam; PF00813; FliP; 1.
DR PRINTS; PR00951; FLGBIOSNFLIP.
DR PRINTS; PR01302; TYPE3IMPPROT.
DR TIGRFAMs; TIGR01103; fliP; 1.
DR PROSITE; PS01060; FLIP_1; 1.
DR PROSITE; PS01061; FLIP_2; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum; Bacterial flagellum biogenesis;
KW Bacterial flagellum protein export; Cell inner membrane; Cell membrane;
KW Membrane; Protein transport; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix; Transport.
FT SIGNAL 1..21
FT /evidence="ECO:0000250"
FT CHAIN 22..245
FT /note="Flagellar biosynthetic protein FliP"
FT /id="PRO_0000042805"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 245 AA; 26928 MW; C8E84B7B10FD1D26 CRC64;
MRRLLSVAPV LLWLITPLAF AQLPGITSQP LPGGGQSWSL PVQTLVFITS LTFIPAILLM
MTSFTRIIIV FGLLRNALGT PSAPPNQVLL GLALFLTFFI MSPVIDKIYV DAYQPFSEEK
ISMQEALEKG AQPLREFMLR QTREADLGLF ARLANTGPLQ GPEAVPMRIL LPAYVTSELK
TAFQIGFTIF IPFLIIDLVI ASVLMALGMM MVPPATIALP FKLMLFVLVD GWQLLVGSLA
QSFYS