ID   FLIP_SALTY              Reviewed;         245 AA.
AC   P54700;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Flagellar biosynthetic protein FliP;
DE   Flags: Precursor;
GN   Name=fliP; Synonyms=flaR; OrderedLocusNames=STM1979;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF N-TERMINUS.
RC   STRAIN=LT2;
RX   PubMed=9324257; DOI=10.1128/jb.179.19.6092-6099.1997;
RA   Ohnishi K., Fan F., Schoenhals G.J., Kihara M., Macnab R.M.;
RT   "The FliO, FliP, FliQ, and FliR proteins of Salmonella typhimurium:
RT   putative components for flagellar assembly.";
RL   J. Bacteriol. 179:6092-6099(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Plays a role in the flagellum-specific transport system.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC       Bacterial flagellum basal body.
CC   -!- MISCELLANEOUS: For insertion of FliP into the membrane, cleavage of the
CC       signal peptide is important kinetically but not absolutely required.
CC   -!- SIMILARITY: Belongs to the FliP/MopC/SpaP family. {ECO:0000305}.
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DR   EMBL; L49021; AAB81319.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20891.1; -; Genomic_DNA.
DR   PIR; S78698; S78698.
DR   RefSeq; NP_460932.1; NC_003197.2.
DR   RefSeq; WP_001253410.1; NC_003197.2.
DR   PDB; 6F2D; EM; 4.20 A; A/B/C/D/E=1-245.
DR   PDB; 7BIN; EM; 3.20 A; A/B/C/D/E=1-245.
DR   PDB; 7CG4; EM; 3.60 A; r/s/t/u/v=1-245.
DR   PDB; 7CGO; EM; 3.90 A; CF/w/x/y/z=1-245.
DR   PDB; 7E80; EM; 3.67 A; CF/w/x/y/z=1-245.
DR   PDBsum; 6F2D; -.
DR   PDBsum; 7BIN; -.
DR   PDBsum; 7CG4; -.
DR   PDBsum; 7CGO; -.
DR   PDBsum; 7E80; -.
DR   AlphaFoldDB; P54700; -.
DR   SMR; P54700; -.
DR   STRING; 99287.STM1979; -.
DR   TCDB; 3.A.6.2.1; the type iii (virulence-related) secretory pathway (iiisp) family.
DR   PaxDb; P54700; -.
DR   EnsemblBacteria; AAL20891; AAL20891; STM1979.
DR   GeneID; 1253500; -.
DR   KEGG; stm:STM1979; -.
DR   PATRIC; fig|99287.12.peg.2096; -.
DR   HOGENOM; CLU_042028_0_1_6; -.
DR   OMA; MPPNQIL; -.
DR   PhylomeDB; P54700; -.
DR   BioCyc; SENT99287:STM1979-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   InterPro; IPR005837; FliP.
DR   InterPro; IPR005838; T3SS_IM_P.
DR   PANTHER; PTHR30587; PTHR30587; 1.
DR   PANTHER; PTHR30587:SF0; PTHR30587:SF0; 1.
DR   Pfam; PF00813; FliP; 1.
DR   PRINTS; PR00951; FLGBIOSNFLIP.
DR   PRINTS; PR01302; TYPE3IMPPROT.
DR   TIGRFAMs; TIGR01103; fliP; 1.
DR   PROSITE; PS01060; FLIP_1; 1.
DR   PROSITE; PS01061; FLIP_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Bacterial flagellum; Bacterial flagellum biogenesis;
KW   Bacterial flagellum protein export; Cell inner membrane; Cell membrane;
KW   Direct protein sequencing; Membrane; Protein transport; Reference proteome;
KW   Signal; Transmembrane; Transmembrane helix; Transport.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000269|PubMed:9324257"
FT   CHAIN           22..245
FT                   /note="Flagellar biosynthetic protein FliP"
FT                   /id="PRO_0000009536"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   245 AA;  26787 MW;  C9A4241F0653A4D4 CRC64;
     MRRLLFLSLA GLWLFSPAAA AQLPGLISQP LAGGGQSWSL SVQTLVFITS LTFLPAILLM
     MTSFTRIIIV FGLLRNALGT PSAPPNQVLL GLALFLTFFI MSPVIDKIYV DAYQPFSEQK
     ISMQEALDKG AQPLRAFMLR QTREADLALF ARLANSGPLQ GPEAVPMRIL LPAYVTSELK
     TAFQIGFTIF IPFLIIDLVI ASVLMALGMM MVPPATIALP FKLMLFVLVD GWQLLMGSLA
     QSFYS