FLIP_TREDE
ID FLIP_TREDE Reviewed; 271 AA.
AC Q9X5A6;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Flagellar biosynthetic protein FliP;
GN Name=fliP; OrderedLocusNames=TDE_2760;
OS Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153
OS / KCTC 15104).
OC Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX NCBI_TaxID=243275;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104;
RA Stamm L.V., Bergen H.L.;
RT "Sequences of the tap1, flgD, flgE, orf4, motA, motB, fliL, fliM, fliY, and
RT fliP Treponema denticola genes.";
RL Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104;
RX PubMed=15064399; DOI=10.1073/pnas.0307639101;
RA Seshadri R., Myers G.S.A., Tettelin H., Eisen J.A., Heidelberg J.F.,
RA Dodson R.J., Davidsen T.M., DeBoy R.T., Fouts D.E., Haft D.H., Selengut J.,
RA Ren Q., Brinkac L.M., Madupu R., Kolonay J.F., Durkin S.A., Daugherty S.C.,
RA Shetty J., Shvartsbeyn A., Gebregeorgis E., Geer K., Tsegaye G.,
RA Malek J.A., Ayodeji B., Shatsman S., McLeod M.P., Smajs D., Howell J.K.,
RA Pal S., Amin A., Vashisth P., McNeill T.Z., Xiang Q., Sodergren E.,
RA Baca E., Weinstock G.M., Norris S.J., Fraser C.M., Paulsen I.T.;
RT "Comparison of the genome of the oral pathogen Treponema denticola with
RT other spirochete genomes.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:5646-5651(2004).
CC -!- FUNCTION: Plays a role in the flagellum-specific transport system.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}. Bacterial flagellum basal body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FliP/MopC/SpaP family. {ECO:0000305}.
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DR EMBL; AF122909; AAD20625.1; -; Genomic_DNA.
DR EMBL; AE017226; AAS13277.1; -; Genomic_DNA.
DR RefSeq; NP_973358.1; NC_002967.9.
DR RefSeq; WP_002680826.1; NC_002967.9.
DR AlphaFoldDB; Q9X5A6; -.
DR SMR; Q9X5A6; -.
DR STRING; 243275.TDE_2760; -.
DR EnsemblBacteria; AAS13277; AAS13277; TDE_2760.
DR GeneID; 2740727; -.
DR KEGG; tde:TDE_2760; -.
DR PATRIC; fig|243275.7.peg.2604; -.
DR eggNOG; COG1338; Bacteria.
DR HOGENOM; CLU_042028_1_0_12; -.
DR OMA; MPPNQIL; -.
DR OrthoDB; 1049349at2; -.
DR Proteomes; UP000008212; Chromosome.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR InterPro; IPR005837; FliP.
DR InterPro; IPR005838; T3SS_IM_P.
DR PANTHER; PTHR30587; PTHR30587; 1.
DR PANTHER; PTHR30587:SF0; PTHR30587:SF0; 1.
DR Pfam; PF00813; FliP; 1.
DR PRINTS; PR00951; FLGBIOSNFLIP.
DR PRINTS; PR01302; TYPE3IMPPROT.
DR TIGRFAMs; TIGR01103; fliP; 1.
DR PROSITE; PS01060; FLIP_1; 1.
DR PROSITE; PS01061; FLIP_2; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum; Bacterial flagellum biogenesis;
KW Bacterial flagellum protein export; Cell membrane; Membrane;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..271
FT /note="Flagellar biosynthetic protein FliP"
FT /id="PRO_0000191989"
FT TRANSMEM 5..25
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 190..210
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 212..232
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 271 AA; 30920 MW; 09D70694B4BB66BD CRC64;
MKKNLLILVF FGMILFIPVQ VFSQSRFPEG TTAGRTDADP NRQAGRIPFI DFSIREPSTN
KDVAFSVQLL IFITLISIAP SLLLLMTSFL RLSIVLDFVK RALSLQQVPP TQVLNGIAFF
LTLFIMWPTF TQIYNNAYKP MSEGQIGIEE AYREAEKPMR YFMYKQMQKN PTHIRTFMAM
SKLPKPDTLA DVPTHILIAA FILHELTIAF QIGIFLYLPF IIIDMIVASI LMSMGMIMLP
PVQISMPFKL ILFVMVDGWG LLFGKLFESF L