ID   FLIP_TREPA              Reviewed;         271 AA.
AC   P74930;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=Flagellar biosynthetic protein FliP;
GN   Name=fliP; OrderedLocusNames=TP_0718;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=8529894; DOI=10.1016/0378-1119(95)00583-x;
RA   Hardham J.M., Frye J.G., Stamm L.V.;
RT   "Identification and sequences of the Treponema pallidum fliM', fliY, fliP,
RT   fliQ, fliR and flhB' genes.";
RL   Gene 166:57-64(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- FUNCTION: Plays a role in the flagellum-specific transport system.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Bacterial flagellum basal body {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FliP/MopC/SpaP family. {ECO:0000305}.
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DR   EMBL; U36839; AAB00546.1; -; Genomic_DNA.
DR   EMBL; AE000520; AAC65684.1; -; Genomic_DNA.
DR   PIR; JC4507; JC4507.
DR   RefSeq; WP_010882163.1; NC_021490.2.
DR   AlphaFoldDB; P74930; -.
DR   SMR; P74930; -.
DR   STRING; 243276.TPANIC_0718; -.
DR   EnsemblBacteria; AAC65684; AAC65684; TP_0718.
DR   GeneID; 57879243; -.
DR   KEGG; tpa:TP_0718; -.
DR   eggNOG; COG1338; Bacteria.
DR   HOGENOM; CLU_042028_1_0_12; -.
DR   OMA; MPPNQIL; -.
DR   OrthoDB; 1049349at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   InterPro; IPR005837; FliP.
DR   InterPro; IPR005838; T3SS_IM_P.
DR   PANTHER; PTHR30587; PTHR30587; 1.
DR   PANTHER; PTHR30587:SF0; PTHR30587:SF0; 1.
DR   Pfam; PF00813; FliP; 1.
DR   PRINTS; PR00951; FLGBIOSNFLIP.
DR   PRINTS; PR01302; TYPE3IMPPROT.
DR   TIGRFAMs; TIGR01103; fliP; 1.
DR   PROSITE; PS01060; FLIP_1; 1.
DR   PROSITE; PS01061; FLIP_2; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Bacterial flagellum biogenesis;
KW   Bacterial flagellum protein export; Cell membrane; Membrane;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..271
FT                   /note="Flagellar biosynthetic protein FliP"
FT                   /id="PRO_0000191990"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        70..90
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   271 AA;  30734 MW;  BBE0138E80C90EF7 CRC64;
     MIRARACVRR ALFFVSLFFF PLFAQDARGG VERGVTGINA ERPASRIPFI NFDIREPQTN
     REVAFSVQLL LLLTLISLAP SILLLMTAFL RLSIVLDFIK RALSLQQVPP TQVLHGIALF
     LALFIMWPVF TEIYAKSFKP LTDGQVDIQT AYTEAERPLR VFMYRQMAHD PSSVRLCMSM
     AKLPKPDTLA DVPTYVLIPA FILHELTVAF QIGIFLYLPF IIVDMVVASI LMSMGMIMLP
     PVQISLPFKL VLFVLVDGWN LLIDRLFHSF L