ID   FLIR_AQUAE              Reviewed;         258 AA.
AC   O67773;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Flagellar biosynthetic protein FliR;
GN   Name=fliR; OrderedLocusNames=aq_1961;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Role in flagellar biosynthesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Bacterial flagellum basal body {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family. {ECO:0000305}.
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DR   EMBL; AE000657; AAC07732.1; -; Genomic_DNA.
DR   PIR; A70468; A70468.
DR   RefSeq; NP_214342.1; NC_000918.1.
DR   RefSeq; WP_010881278.1; NC_000918.1.
DR   AlphaFoldDB; O67773; -.
DR   SMR; O67773; -.
DR   STRING; 224324.aq_1961; -.
DR   EnsemblBacteria; AAC07732; AAC07732; aq_1961.
DR   KEGG; aae:aq_1961; -.
DR   PATRIC; fig|224324.8.peg.1512; -.
DR   eggNOG; COG1684; Bacteria.
DR   HOGENOM; CLU_063626_2_2_0; -.
DR   InParanoid; O67773; -.
DR   OMA; APQFNIF; -.
DR   OrthoDB; 1942709at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR   InterPro; IPR006303; FliR.
DR   InterPro; IPR002010; T3SS_IM_R.
DR   PANTHER; PTHR30065; PTHR30065; 1.
DR   Pfam; PF01311; Bac_export_1; 1.
DR   PRINTS; PR00953; TYPE3IMRPROT.
DR   TIGRFAMs; TIGR01400; fliR; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..258
FT                   /note="Flagellar biosynthetic protein FliR"
FT                   /id="PRO_0000192048"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        125..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   258 AA;  29178 MW;  F17CE7B57D639F3B CRC64;
     MDKVTSEEFL ITLLLSYFRI VSFLFTFPFY GSFLIPNTIR LYLAFALSFA VLSFINITPV
     KVNTFVEFLV YALNELLFGF SAGLILRLLF DALIIAGELI ALHTGLGFLQ MFIPGMTQMS
     LFSGFFTLYG TLIFLSLGGG EFIILGLAES FKRLPVGSFN IFYLNPEVFL NFFYESFRLG
     VKIAMPLILT ALILNLVLAV VNRFIPQMNV FMVGLPLQVS IGLIILLLSL PLITITMSNH
     FQDFFKVFEY FIQSFKSP