FLIR_BACSU
ID FLIR_BACSU Reviewed; 259 AA.
AC P35537;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 2.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Flagellar biosynthetic protein FliR;
GN Name=fliR; OrderedLocusNames=BSU16370;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / OI1085;
RX PubMed=8299954; DOI=10.1016/0378-1119(93)90014-t;
RA Carpenter P.B., Zuberi A.R., Ordal G.W.;
RT "Bacillus subtilis flagellar proteins FliP, FliQ, FliR and FlhB are related
RT to Shigella flexneri virulence factors.";
RL Gene 137:243-245(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP SEQUENCE REVISION TO 165 AND 174.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
CC -!- FUNCTION: Role in flagellar biosynthesis.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}. Bacterial flagellum basal body {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X74122; CAA52219.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB13510.2; -; Genomic_DNA.
DR EMBL; M87005; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; I40401; I40401.
DR RefSeq; NP_389519.2; NC_000964.3.
DR RefSeq; WP_003245510.1; NZ_JNCM01000035.1.
DR AlphaFoldDB; P35537; -.
DR SMR; P35537; -.
DR STRING; 224308.BSU16370; -.
DR PaxDb; P35537; -.
DR PRIDE; P35537; -.
DR EnsemblBacteria; CAB13510; CAB13510; BSU_16370.
DR GeneID; 940130; -.
DR KEGG; bsu:BSU16370; -.
DR PATRIC; fig|224308.179.peg.1778; -.
DR eggNOG; COG1684; Bacteria.
DR InParanoid; P35537; -.
DR OMA; APQFNIF; -.
DR PhylomeDB; P35537; -.
DR BioCyc; BSUB:BSU16370-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IMP:CACAO.
DR GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IMP:CACAO.
DR GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR InterPro; IPR006303; FliR.
DR InterPro; IPR002010; T3SS_IM_R.
DR PANTHER; PTHR30065; PTHR30065; 1.
DR Pfam; PF01311; Bac_export_1; 1.
DR PRINTS; PR00953; TYPE3IMRPROT.
DR TIGRFAMs; TIGR01400; fliR; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..259
FT /note="Flagellar biosynthetic protein FliR"
FT /id="PRO_0000192049"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 165
FT /note="K -> Q (in Ref. 1; CAA52219)"
FT /evidence="ECO:0000305"
FT CONFLICT 174
FT /note="F -> L (in Ref. 1; CAA52219)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 259 AA; 28636 MW; F589D8E3346C8E70 CRC64;
MNSIIDLFPA FLLVFIRISA FFVTIPLFGH RNVPAVHRIG FAFFLAVICF STIDKPPSLE
IDEHYMLLAF KEALVGLCLG LIAYMMIAAV QIAGSFIDFQ MGFSIANVID PQTGAQSPLI
GQFIYTMALL FMLSVNAHHL LLDGIYYSFQ YISVDQAFPN FGDEKFAYFI AKSFNAMFII
AFQMSAPVVA SLFLVDLALG IVARTVPQLN VFVVGLPLKI AVSFIMLIVC MSVIFVVVRN
VFSLTIETMR NLLALVGVS
