ID   FLIR_CAUVC              Reviewed;         251 AA.
AC   Q45975;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Flagellar biosynthetic protein FliR;
GN   Name=fliR; OrderedLocusNames=CC_1076;
OS   Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=190650;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15;
RX   PubMed=7814323; DOI=10.1128/jb.177.2.343-356.1995;
RA   Zhuang W.Y., Shapiro L.;
RT   "Caulobacter FliQ and FliR membrane proteins, required for flagellar
RT   biogenesis and cell division, belong to a family of virulence factor export
RT   proteins.";
RL   J. Bacteriol. 177:343-356(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19089 / CB15;
RX   PubMed=11259647; DOI=10.1073/pnas.061029298;
RA   Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA   Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA   Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA   DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA   Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA   Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA   Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT   "Complete genome sequence of Caulobacter crescentus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC   -!- FUNCTION: Role in flagellar biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}. Bacterial flagellum basal body {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family. {ECO:0000305}.
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DR   EMBL; U13663; AAA66207.1; -; Genomic_DNA.
DR   EMBL; AE005673; AAK23060.1; -; Genomic_DNA.
DR   PIR; I40671; I40671.
DR   RefSeq; NP_419892.1; NC_002696.2.
DR   RefSeq; WP_010918960.1; NC_002696.2.
DR   AlphaFoldDB; Q45975; -.
DR   SMR; Q45975; -.
DR   STRING; 190650.CC_1076; -.
DR   EnsemblBacteria; AAK23060; AAK23060; CC_1076.
DR   KEGG; ccr:CC_1076; -.
DR   PATRIC; fig|190650.5.peg.1094; -.
DR   eggNOG; COG1684; Bacteria.
DR   HOGENOM; CLU_063626_3_0_5; -.
DR   OMA; APQFNIF; -.
DR   BioCyc; CAULO:CC1076-MON; -.
DR   Proteomes; UP000001816; Chromosome.
DR   GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR   GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR   InterPro; IPR006303; FliR.
DR   InterPro; IPR002010; T3SS_IM_R.
DR   PANTHER; PTHR30065; PTHR30065; 1.
DR   Pfam; PF01311; Bac_export_1; 1.
DR   PRINTS; PR00953; TYPE3IMRPROT.
DR   TIGRFAMs; TIGR01400; fliR; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..251
FT                   /note="Flagellar biosynthetic protein FliR"
FT                   /id="PRO_0000192054"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   251 AA;  26413 MW;  8DA48FCC0BA08ECE CRC64;
     MNAFATAFQV YVAALVFARV GAMVMTMPGI GDQAIPARIR LSFALLMALI LAPLVQNTVG
     PIPSTLGGLG GAVIHEVLIG LMIGSVLRLF MTSLTTAGEI ISMQTTLSFA QSTNPSMEGS
     STAVATFLSM LGLTLVMATD LHHLFIAAIV KSYTIFPFTR AVPVNDAAAL AVQTVAQSFS
     LGVQLAAPVI VFSLVFNLAT GLVGRIMPAF QIFFVASPLS VILGLSLLAL SLSGIAMVWT
     DRYRELLDIF T