FLIR_SALTY
ID FLIR_SALTY Reviewed; 264 AA.
AC P54702;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2002, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Flagellar biosynthetic protein FliR;
GN Name=fliR; Synonyms=flaP; OrderedLocusNames=STM1981;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=9324257; DOI=10.1128/jb.179.19.6092-6099.1997;
RA Ohnishi K., Fan F., Schoenhals G.J., Kihara M., Macnab R.M.;
RT "The FliO, FliP, FliQ, and FliR proteins of Salmonella typhimurium:
RT putative components for flagellar assembly.";
RL J. Bacteriol. 179:6092-6099(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Role in flagellar biosynthesis.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC Bacterial flagellum basal body.
CC -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family. {ECO:0000305}.
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DR EMBL; L49021; AAB81321.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL20893.1; -; Genomic_DNA.
DR PIR; S78700; S78700.
DR RefSeq; NP_460934.1; NC_003197.2.
DR RefSeq; WP_000616953.1; NC_003197.2.
DR PDB; 6F2D; EM; 4.20 A; F=1-264.
DR PDB; 6R69; EM; 3.65 A; F=1-264.
DR PDB; 7BIN; EM; 3.20 A; F=1-264.
DR PDB; 7CGO; EM; 3.90 A; CE=1-264.
DR PDB; 7E80; EM; 3.67 A; CE=1-264.
DR PDBsum; 6F2D; -.
DR PDBsum; 6R69; -.
DR PDBsum; 7BIN; -.
DR PDBsum; 7CGO; -.
DR PDBsum; 7E80; -.
DR AlphaFoldDB; P54702; -.
DR SMR; P54702; -.
DR STRING; 99287.STM1981; -.
DR TCDB; 3.A.6.2.1; the type iii (virulence-related) secretory pathway (iiisp) family.
DR PaxDb; P54702; -.
DR EnsemblBacteria; AAL20893; AAL20893; STM1981.
DR GeneID; 1253502; -.
DR KEGG; stm:STM1981; -.
DR PATRIC; fig|99287.12.peg.2098; -.
DR HOGENOM; CLU_063626_4_0_6; -.
DR OMA; APQFNIF; -.
DR PhylomeDB; P54702; -.
DR BioCyc; SENT99287:STM1981-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR InterPro; IPR006303; FliR.
DR InterPro; IPR002010; T3SS_IM_R.
DR PANTHER; PTHR30065; PTHR30065; 1.
DR Pfam; PF01311; Bac_export_1; 1.
DR PRINTS; PR00953; TYPE3IMRPROT.
DR TIGRFAMs; TIGR01400; fliR; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Bacterial flagellum; Cell inner membrane; Cell membrane;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..264
FT /note="Flagellar biosynthetic protein FliR"
FT /id="PRO_0000192056"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 66..86
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 24
FT /note="L -> R (in Ref. 1; AAB81321)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 264 AA; 28925 MW; 7AFF46906147A63F CRC64;
MIQVTSEQWL YWLHLYFWPL LRVLALISTA PILSERAIPK RVKLGLGIMI TLVIAPSLPA
NDTPLFSIAA LWLAMQQILI GIALGFTMQF AFAAVRTAGE FIGLQMGLSF ATFVDPGSHL
NMPVLARIMD MLAMLLFLTF NGHLWLISLL VDTFHTLPIG SNPVNSNAFM ALARAGGLIF
LNGLMLALPV ITLLLTLNLA LGLLNRMAPQ LSIFVIGFPL TLTVGIMLMA ALMPLIAPFC
EHLFSEIFNL LADIVSEMPI NNNP
