FLIW_BORRA
ID FLIW_BORRA Reviewed; 130 AA.
AC B5RR02;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 04-NOV-2008, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Flagellar assembly factor FliW {ECO:0000255|HAMAP-Rule:MF_01185};
GN Name=fliW {ECO:0000255|HAMAP-Rule:MF_01185}; OrderedLocusNames=BRE_181;
OS Borrelia recurrentis (strain A1).
OC Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borrelia.
OX NCBI_TaxID=412418;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A1;
RX PubMed=18787695; DOI=10.1371/journal.pgen.1000185;
RA Lescot M., Audic S., Robert C., Nguyen T.T., Blanc G., Cutler S.J.,
RA Wincker P., Couloux A., Claverie J.-M., Raoult D., Drancourt M.;
RT "The genome of Borrelia recurrentis, the agent of deadly louse-borne
RT relapsing fever, is a degraded subset of tick-borne Borrelia duttonii.";
RL PLoS Genet. 4:E1000185-E1000185(2008).
CC -!- FUNCTION: Acts as an anti-CsrA protein, binds CsrA and prevents it from
CC repressing translation of its target genes, one of which is flagellin.
CC Binds to flagellin and participates in the assembly of the flagellum.
CC {ECO:0000255|HAMAP-Rule:MF_01185}.
CC -!- SUBUNIT: Interacts with translational regulator CsrA and flagellin(s).
CC {ECO:0000255|HAMAP-Rule:MF_01185}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01185}.
CC -!- SIMILARITY: Belongs to the FliW family. {ECO:0000255|HAMAP-
CC Rule:MF_01185}.
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DR EMBL; CP000993; ACH94436.1; -; Genomic_DNA.
DR RefSeq; WP_012537950.1; NC_011244.1.
DR AlphaFoldDB; B5RR02; -.
DR SMR; B5RR02; -.
DR PRIDE; B5RR02; -.
DR EnsemblBacteria; ACH94436; ACH94436; BRE_181.
DR KEGG; bre:BRE_181; -.
DR HOGENOM; CLU_112356_0_2_12; -.
DR OMA; NIEEKDW; -.
DR OrthoDB; 1767625at2; -.
DR Proteomes; UP000000612; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR Gene3D; 2.30.290.10; -; 1.
DR HAMAP; MF_01185; FliW; 1.
DR InterPro; IPR003775; Flagellar_assembly_factor_FliW.
DR InterPro; IPR024046; Flagellar_assmbl_FliW_dom_sf.
DR PANTHER; PTHR39190; PTHR39190; 1.
DR Pfam; PF02623; FliW; 1.
DR SUPFAM; SSF141457; SSF141457; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis; Chaperone; Cytoplasm;
KW Translation regulation.
FT CHAIN 1..130
FT /note="Flagellar assembly factor FliW"
FT /id="PRO_1000138252"
SQ SEQUENCE 130 AA; 15275 MW; 110C8D1CF816AF33 CRC64;
MKNKFSIKVK FPEGILGFED IKEFIIKDSA HKPFSIMQSI NGEINFLVTS PFNFLEKYLP
NIENKDWLDI QAENENEKVI LCIINMHVKN YKEITANLKA PIILNKKKLI GKQAISTNEE
HYLRYRVFKE