ID   FLIZ_BACSU              Reviewed;         219 AA.
AC   P35536;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Flagellar biosynthetic protein FliZ;
DE   Flags: Precursor;
GN   Name=fliZ; Synonyms=cheA; OrderedLocusNames=BSU16340;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / OI1085;
RX   PubMed=1597417; DOI=10.1128/jb.174.12.4017-4025.1992;
RA   Bischoff D.S., Weinreich M.D., Ordal G.W.;
RT   "Nucleotide sequences of Bacillus subtilis flagellar biosynthetic genes
RT   fliP and fliQ and identification of a novel flagellar gene, fliZ.";
RL   J. Bacteriol. 174:4017-4025(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: May be a structural component of the flagellum that anchors
CC       the rod to the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; M87005; AAA22452.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB13507.1; -; Genomic_DNA.
DR   PIR; B41886; B41886.
DR   RefSeq; NP_389516.1; NC_000964.3.
DR   RefSeq; WP_003231958.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; P35536; -.
DR   IntAct; P35536; 13.
DR   STRING; 224308.BSU16340; -.
DR   PaxDb; P35536; -.
DR   PRIDE; P35536; -.
DR   EnsemblBacteria; CAB13507; CAB13507; BSU_16340.
DR   GeneID; 936796; -.
DR   KEGG; bsu:BSU16340; -.
DR   PATRIC; fig|224308.179.peg.1775; -.
DR   eggNOG; COG3190; Bacteria.
DR   OMA; LMNKRNR; -.
DR   BioCyc; BSUB:BSU16340-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0044781; P:bacterial-type flagellum organization; IEA:UniProtKB-KW.
DR   InterPro; IPR022781; Flagellar_biosynth_FliO.
DR   Pfam; PF04347; FliO; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum biogenesis; Cell membrane; Membrane;
KW   Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..219
FT                   /note="Flagellar biosynthetic protein FliZ"
FT                   /id="PRO_0000021272"
FT   TRANSMEM        71..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          41..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          200..219
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..61
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   219 AA;  24871 MW;  6FE82AF8E1DAEE8E CRC64;
     MKKSQYFIVF ICFFVLFSVH PIAAAAADSD NSTVNEWFQK KDEKTADQSE QKKEKTTKTA
     DETEGAAAPS VSAFDFVKMI FALLFVIVLI YGLVKLMNKR NRLLKPFQYV ENIGGTSVGQ
     NRSIQLIKVG KSVLVVGVGE TIQLLKEIED EKEIEVILSQ HEEAMSSKIE WQKFVKPLKS
     SEHQPQQKLP SFSKALKEQL EELKQNRSEG KKKGPRHHE