ID   FLOA1_RHOBA             Reviewed;         345 AA.
AC   Q7UQJ2;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Flotillin-like protein FloA 1 {ECO:0000255|HAMAP-Rule:MF_01562};
GN   Name=floA1 {ECO:0000255|HAMAP-Rule:MF_01562}; OrderedLocusNames=RB6291;
OS   Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1).
OC   Bacteria; Planctomycetes; Planctomycetia; Pirellulales; Pirellulaceae;
OC   Rhodopirellula.
OX   NCBI_TaxID=243090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10527 / NCIMB 13988 / SH1;
RX   PubMed=12835416; DOI=10.1073/pnas.1431443100;
RA   Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W.,
RA   Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R.,
RA   Reinhardt R.;
RT   "Complete genome sequence of the marine planctomycete Pirellula sp. strain
RT   1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003).
CC   -!- FUNCTION: Found in functional membrane microdomains (FMM) that may be
CC       equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and
CC       increase in number as cells age. Flotillins are thought to be important
CC       factors in membrane fluidity. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBUNIT: Homooligomerizes. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01562};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC       Membrane raft {ECO:0000255|HAMAP-Rule:MF_01562}; Single-pass membrane
CC       protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SIMILARITY: Belongs to the flotillin-like FloA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01562}.
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DR   EMBL; BX294143; CAD74711.1; -; Genomic_DNA.
DR   RefSeq; NP_867166.1; NC_005027.1.
DR   RefSeq; WP_007327752.1; NC_005027.1.
DR   AlphaFoldDB; Q7UQJ2; -.
DR   SMR; Q7UQJ2; -.
DR   STRING; 243090.RB6291; -.
DR   PRIDE; Q7UQJ2; -.
DR   EnsemblBacteria; CAD74711; CAD74711; RB6291.
DR   KEGG; rba:RB6291; -.
DR   PATRIC; fig|243090.15.peg.3033; -.
DR   eggNOG; COG4864; Bacteria.
DR   HOGENOM; CLU_836378_0_0_0; -.
DR   OMA; WFQAFMS; -.
DR   OrthoDB; 827327at2; -.
DR   Proteomes; UP000001025; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01562; FloA; 1.
DR   InterPro; IPR022853; FloA.
DR   Pfam; PF12127; YdfA_immunity; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..345
FT                   /note="Flotillin-like protein FloA 1"
FT                   /id="PRO_0000232558"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01562"
SQ   SEQUENCE   345 AA;  37257 MW;  C7E05AC004CF9515 CRC64;
     MAMIDLTHDW QLLAQNPAGG LNSSSLLLLV GVFLALFFAA VLGFFFLRYG KLWFQAFMSD
     ADVQLLNLIR MHFTKVNPNV IVQAKVMVAQ AGLNIGRRDG ISTHRLEAHY LAGGNVMNVI
     HAIIAAHRAQ IPLEFDQAAA IDLAGRDVLD AVQTSVYPKV IDCPDPKRSG KTTLSAITKN
     GVELRVRTRV TVRTNIEQLI GGATEDTVIA RVGEAIISSI GSAETHFKVL ENPDMITRVV
     LSRGLDAQTA FEIVSIDIAD IDVGENIGAR LQNDQAEADT RVARAQAERR RAEAIAAEQQ
     MNARVSENRS RLVLAEADVP RALAEAFKAG RIGNVSSVAA AEGSA