ID   FLOA2_RHOBA             Reviewed;         362 AA.
AC   Q7UQD2;
DT   18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Flotillin-like protein FloA 2 {ECO:0000255|HAMAP-Rule:MF_01562};
GN   Name=floA2 {ECO:0000255|HAMAP-Rule:MF_01562}; OrderedLocusNames=RB6389;
OS   Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1).
OC   Bacteria; Planctomycetes; Planctomycetia; Pirellulales; Pirellulaceae;
OC   Rhodopirellula.
OX   NCBI_TaxID=243090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10527 / NCIMB 13988 / SH1;
RX   PubMed=12835416; DOI=10.1073/pnas.1431443100;
RA   Gloeckner F.O., Kube M., Bauer M., Teeling H., Lombardot T., Ludwig W.,
RA   Gade D., Beck A., Borzym K., Heitmann K., Rabus R., Schlesner H., Amann R.,
RA   Reinhardt R.;
RT   "Complete genome sequence of the marine planctomycete Pirellula sp. strain
RT   1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:8298-8303(2003).
CC   -!- FUNCTION: Found in functional membrane microdomains (FMM) that may be
CC       equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and
CC       increase in number as cells age. Flotillins are thought to be important
CC       factors in membrane fluidity. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBUNIT: Homooligomerizes. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01562};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC       Membrane raft {ECO:0000255|HAMAP-Rule:MF_01562}; Single-pass membrane
CC       protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SIMILARITY: Belongs to the flotillin-like FloA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01562}.
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DR   EMBL; BX294144; CAD74771.1; -; Genomic_DNA.
DR   RefSeq; NP_867226.1; NC_005027.1.
DR   AlphaFoldDB; Q7UQD2; -.
DR   SMR; Q7UQD2; -.
DR   STRING; 243090.RB6389; -.
DR   PRIDE; Q7UQD2; -.
DR   EnsemblBacteria; CAD74771; CAD74771; RB6389.
DR   KEGG; rba:RB6389; -.
DR   PATRIC; fig|243090.15.peg.3088; -.
DR   eggNOG; COG4864; Bacteria.
DR   HOGENOM; CLU_836378_0_0_0; -.
DR   InParanoid; Q7UQD2; -.
DR   OMA; GIMDYYR; -.
DR   OrthoDB; 827327at2; -.
DR   Proteomes; UP000001025; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01562; FloA; 1.
DR   InterPro; IPR022853; FloA.
DR   Pfam; PF12127; YdfA_immunity; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..362
FT                   /note="Flotillin-like protein FloA 2"
FT                   /id="PRO_0000232557"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01562"
SQ   SEQUENCE   362 AA;  38691 MW;  D6371EB052F770AE CRC64;
     MRRPMIASLL LDTLPLAQMP KVTTALLIGA LVIFAGIVVV LFIFTSYFGL WIQSVLTGSK
     ISFGNLIGMT FRKVNTRAIV RSKIMATQAG LDDPELTVGA LEAHYLAGGN VQQVIRALIA
     AKKAKTISLT FREATAIDLA GRDVLESVQT SVYPKVIDCP PRGSAKPSLD AVAKDGIQLK
     VRARVTVRAN LQQLIGGATE ETIIARVGEG IVSAIGSADD HKAVLENPDV ISKAVLVKKL
     DSQTAFEIVS IDIADIDVGA NIGARLQADQ AEADTAVARA NAEGRRAAAV AEEQEMQAEI
     AKSQAQVVEA QSDVPRAMAE AFRSGKLLVM DYYRLQNVSA DTEMRRALAG HSHDPDTPEE
     TH