ID   FLOA_DICTD              Reviewed;         329 AA.
AC   B8DZW4;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Flotillin-like protein FloA {ECO:0000255|HAMAP-Rule:MF_01562};
GN   Name=floA {ECO:0000255|HAMAP-Rule:MF_01562}; OrderedLocusNames=Dtur_0765;
OS   Dictyoglomus turgidum (strain DSM 6724 / Z-1310).
OC   Bacteria; Dictyoglomi; Dictyoglomales; Dictyoglomaceae; Dictyoglomus.
OX   NCBI_TaxID=515635;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6724 / Z-1310;
RX   PubMed=28066333; DOI=10.3389/fmicb.2016.01979;
RA   Brumm P.J., Gowda K., Robb F.T., Mead D.A.;
RT   "The complete genome sequence of hyperthermophile Dictyoglomus turgidum DSM
RT   6724 reveals a specialized carbohydrate fermentor.";
RL   Front. Microbiol. 7:1979-1979(2016).
CC   -!- FUNCTION: Found in functional membrane microdomains (FMM) that may be
CC       equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and
CC       increase in number as cells age. Flotillins are thought to be important
CC       factors in membrane fluidity. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBUNIT: Homooligomerizes. {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01562};
CC       Single-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC       Membrane raft {ECO:0000255|HAMAP-Rule:MF_01562}; Single-pass membrane
CC       protein {ECO:0000255|HAMAP-Rule:MF_01562}.
CC   -!- SIMILARITY: Belongs to the flotillin-like FloA family.
CC       {ECO:0000255|HAMAP-Rule:MF_01562}.
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DR   EMBL; CP001251; ACK42047.1; -; Genomic_DNA.
DR   RefSeq; WP_012583132.1; NC_011661.1.
DR   RefSeq; YP_002352661.1; NC_011661.1.
DR   AlphaFoldDB; B8DZW4; -.
DR   SMR; B8DZW4; -.
DR   STRING; 515635.Dtur_0765; -.
DR   EnsemblBacteria; ACK42047; ACK42047; Dtur_0765.
DR   KEGG; dtu:Dtur_0765; -.
DR   PATRIC; fig|515635.4.peg.802; -.
DR   eggNOG; COG4864; Bacteria.
DR   HOGENOM; CLU_836378_0_0_0; -.
DR   InParanoid; B8DZW4; -.
DR   OMA; GIMDYYR; -.
DR   OrthoDB; 827327at2; -.
DR   Proteomes; UP000007719; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01562; FloA; 1.
DR   InterPro; IPR022853; FloA.
DR   Pfam; PF12127; YdfA_immunity; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..329
FT                   /note="Flotillin-like protein FloA"
FT                   /id="PRO_1000199713"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01562"
SQ   SEQUENCE   329 AA;  35210 MW;  F0FEF50156C4AFB1 CRC64;
     MNLIWGFLIL ILVLIFLGVF FSFVPLGLWI SALAAGVSIR ITDLIGMRLR RVPPGVIINS
     LIKAHKAGLS EVTLDKLEAH YLAGGNVDKV VNALIAAQRA GIPLTFEKAA AIDLAGRDVL
     EAVQMSVNPK VIETPVVAAV AKDGIELKAK ARVTVRANIE RLVGGAGEAT IIARVGEGIV
     TTIGSAESYK EVLENPDSIS KTVLAKGLDA GTAFEIVSID IADVDVGNNV GARLKMDQAE
     ADMRIAQAQA ESRRALAIAR EQEMKALTQE MRARLIEAEK EVPLAIAEAL RSGKIGVLDY
     YTLKNIIADT AMREAISKLG QKEEEGRKD